PSA climbing

[Pizzle123]

Been a while since I posted, Long story short. Radiation 2019/2020. Psa was lower than a snakes guts. then it started to rise and was advised by urologist to have salvage surgery. Our friend TA advised against this. Sorry TA but to keep my Sheriff happy went through with it on 15 february 2023. I ended up with a staf infection and had 2 weeks in hospital then 2 weeks at home visiting hospital every day to have my intravenos antibiotic changed. since then I have had a pain where the prostate used to be. Uro's say take panadol and nurofen. waste of time . Purely by accident I found that anti inflammatory pills do the job. 2024: PSA rose rapidly to 3.8 and the oncologist has put me back on ADT [eligard]. I've had 2 Pet PSMA scans in 12 months and it shows absolutely nothing. My question is, what could possibly be causing my psa to rise rapidly?

[Xavier10]

When they took what remained of your prostate out, surely they analyzed it. Anything? Maybe a different type of scan is necessary. there are a few types of PCa that don't light up with PSMA

[Pizzle123 in reply to Xavier10]

This is something I will be asking my Oncologist when i talk to him in march. I need to go prepared this time

[Tall_Allen]

Too bad your "sheriff" had an opinion. You have to have whole pelvic radiation + 2 years of ADT to get the micromets in that area. Unfortunately, the radiation on top of the surgery will probably have urinary side effects. Maybe a few months of ADT before radiation starts will give it a chance to heal.

[Pizzle123 in reply to Tall_Allen]

Thanks for your reply Tall_Allen. They tell me I cannot have radiation again. I already have incontenience since my visit to hospital with the staf infection. The Dr that was on when I was admitted insisted that I have a catheter in against my wishes i might add as the prostate had been removed 3 weeks prior. I had no incontenience issue before that. then it was UTI's consistantly for about 3 months during which time I had to self catheter 4 to 5 times a day. I"m almost ready to throw the towel in. I'm 68 years old and had a gutful.

[petabyte in reply to Pizzle123]

I was just listening to a podcast yesterday where a well known professor of radiation oncology mentioned re irradiation as one of the better options for recurrence. But ofc it depends on the individual case.

Btw I don't understand the Sheriff reference.

youtu.be/xZYMTRjKI9U(Not working as expected?)

[Tall_Allen in reply to Pizzle123]

I hope there is a special place in Hell for your urologist.