Allendronic Acid and Cholesterol : Telephone... - PMRGCAuk

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Allendronic Acid and Cholesterol

Mazxstitch profile image
14 Replies

Telephone consultation this morning went as I thought it would. What dosage of Prednisolone are you on? 2.75mg I answered.

So you will be coming down to 2mg?

No, I taper by a quarter of a mg every 5 weeks. I will be tapering to 2.5mg.

And so it went on!

I am advised that I need to start taking Allendronic Acid. A Dexa scan wasn't necessary as I am 78 years old.

She also wants me to start taking Statins.

I don't want to take more medications, neither do I want to change my taper. I started it on the 9th August 2023 and have had no problems.

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Mazxstitch profile image
Mazxstitch
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14 Replies
DorsetLady profile image
DorsetLadyPMRGCAuk volunteer

Don’t really see the point of adding in AA when you are so low on Pred -has she just read the guidelines? 🙄

Are you on a VitD/Calcium -if so, many find that’s enough. If not, perhaps suggest she prescribes it.,,

As for statins -is that from a recent cholesterol test? And that’s your choice whether to take them , some get on fine with them, some don’t. I’d want more information why she thinks they are required -and it’s not just a tick the box exercise.

Mazxstitch profile image
Mazxstitch in reply to DorsetLady

Thank you, DorsetLady for your reply.I take VitD and calcium, always have.

Yes, I had a recent blood test and cholesterol is 6.4.

A pharmacist is going to phone me this month to explain the AA and statins.

I think she was just "ticking the boxes".

I have more confidence in what I read here, than advice from doctors.

DorsetLady profile image
DorsetLadyPMRGCAuk volunteer in reply to Mazxstitch

Cholesterol is a bit high… so can understand her issue.. I have had the same in the past [not quite as high as yours].

I did take statins for about 20 years in my 50s and 60s [needed to try 3 different types] but for some reason now in my 70s I am definitely intolerant… have tried different ones again over the 3 years. .. no go! So now noted on my records. Since last round of annual tests have decided to try plant sterols to see if they help - others on here reckon they do.

Even though guidelines state for over 65s there is no need DEXA to see if AA required… why take something if you don’t need to. I took them for 4 years [family and personal reasons] with no issues - but some have issues with them.

See what pharmacist says…

random901 profile image
random901

Hi Mazxstitch. I have refused both statins and alendronic acid. Both can cause problems, and I'm already on a cocktail of meds to which I don't want to add more. Instead, I'm careful with diet, eating lots of cooked tomatoes, and kefir or thick yoghurt plus calcium-rich foods, lots of oily fish. No broken bones yet. Just tapered from 15mg pred to 12.5. It's your body - stand your ground! Best wishes.

PMRpro profile image
PMRproAmbassador

Adding AA without proof of need at this stage is questionable - especially as your dose is so low so soon. The mean time to 5mg from 15mg is about 18 months. I had been on pred at far higher doses for 14+ years before a possible spinal compression fracture meant I agreed to an annual infusion starting last January.

Statins - can't help there much as the two I tried didn't do me any good at all, nearly in a wheelchair with one and a massive PMR flare after starting the second. Correlation is not causation but I'm really not prepared to risk it - and neither is my rheumy. Cardiology were very relaxed about it in general.

Charlie892 profile image
Charlie892

As you are 78, the evidence for statins helping with anything , unless you have pre-existing cardiovascular problems is very poor. I would refuse.

PMRpro profile image
PMRproAmbassador in reply to Charlie892

There is recent work that shows there is more benefit than previously thought

healthline.com/health-news/...

Thelmarina profile image
Thelmarina in reply to PMRpro

Thanks for that link. Interesting. Also reassuring that all this research is taking place behind the scenes with nothing taken for granted.

Charlie892 profile image
Charlie892

"but more research is needed" seems to be the conclusion of this recent work. I would tend to wait for the research. Big Pharma will continue to push statins, they have a lot to lose if statins are actually shown not to do a lot. I recommend the books by Malcolm Kendrick eg The Clot Thickens and Doctoring Data. He has recently won a libel case against the Daily Mail who accused him of being a "statin denier" (I know, no one in their right mind would believe what's published in this paper, but still....)

PMRpro profile image
PMRproAmbassador in reply to Charlie892

Handy source of income though!!!

ALL controversial studies end with "More research required" - standard conclusion for most if it comes to that. No-one wants to be thought arrogant enough to think their work is definitive!!!! That is for others to decide ...

piglette profile image
piglette

Sounds like my GP. Hands out drugs for the sake of it. I know more about pharmaceuticals than he does!

WaltzG profile image
WaltzG

Been refusing statins for years. Cholesterol levels control with diet and exercise...evidence of effectiveness for women is still unproven. Hold firm !!

ChrisBeeLoop profile image
ChrisBeeLoop

I refused AA, even though I discussed it with my dentist and he said the dosage was low enough that it was unlikely to cause deterioration in the jaw bones. However, I saw him again this week and he advised to stay well clear of it.

I insisted that my GP gave me a DEXA scan. She said not until your Preds course is finished so they can measure the degree of damage to the bones. I insisted saying I wanted a base line measurement. Eventually she gave in. It is a cheap and easy procedure, no reason why they should not make it more available. The result was that my bone density was spot on normal for a 30 year old. I am 75. I eat lots of yoghurt and cheese, and meat.

There were three questions she asked before the scan. Had I experienced any fractures before? Was there a family history of broken bones or fractures? Had I experienced an early menopause? All three answers were no. I suspect if you say yes it will help you GP make the right decision. Two final options, ask to see a different GP, they can't refuse if there is one in the surgery, or go privately. It is not hugely expensive. Good luck and good health!

Missus835 profile image
Missus835

Since March, my cholesterol has gone up to 7.4. Isn't it interesting that I have bloods done monthly and GP now says "it's serious". I can't even figure out why it's rising steadily. Regardless, after fending off the statins for quite awhile, I've started on rosuvastatin 10 mg which gives me the bending over stomach cramps and diarrhea. For me, diarrhea may be an okay thing as I have chronic constipation from codeine. Another long story. Anyway, this will be my third day and if the cramps persist (or any other pain) I'll have to give her a ring. This morning I will take with food to see if it helps with the stomach upset. Also, a generally crappy feeling for most of the day and very little appetite. As for AA I could never tolerate it, but I do now have severe osteoporosis, for which the rheumy was a year late with her diagnosis. I had a Zoledronic Acid infusion done last October, but have fractured another vertebrae about one month ago. Need another dexascan, but Osteo Specialist says we only do them every three years now, here In Nova Scotia. I wanted to know if there had been any improvement at all. This was my suggestion, so maybe she didn't like it.

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