Thanks to all who advised me on my new Lefluonomide intake. I have separated the PRED- take, some time ago, to early am -the Thyroxine to evening meal time- because of interaction(I had no problems) and advice (this column- indirectly) .I have looked everywhere for info when to take Lefluonomide - the consultant did not advise-they do not seem to advise generally 'Holistically' .On the morrow am I have my 1st blood take and will be taking the LEFLU. when - guidance would be welcome please. John