I haven’t posted here for a while but now find I need some advice please. I was diagnosed with PMR 2 years ago and I have recently begun reducing to 4mg from 4 ½ mg prednisone using the dead slow & stop method. Apart from experiencing prednisone withdrawal symptoms during this time the reductions have been reasonably smooth. However, while reducing to 4mg I was beginning to have little ‘ niggles’ such as mild buttock pain & stiffness. I haven’t needed to go for blood tests using the ‘ standing order’ blood test sheet my GP gave me in the early days of reducing to enable me to monitor the ESR & CRP rates but I decided to have the test done yesterday and have the results back. At the beginning of the PMR diagnosis the rates were : ESR 22 & CRP 46. After starting the Prednisone treatment the readings have been consistent for 18months at : ESR 2 & CRP 10 . However, yesterday’s results are : ESR 11 & CRP 10 which means the ESR rate has increased quite a bit. I won’t be able to see my GP for advice until next week. Do you think I should stop the reduction and if so what dose of Pred should I return to? Even though I don’t feel too bad I wonder if this is an indication that I still have the PMR and should stick to a dose of maybe 5 mg for a while ? I would appreciate your advice please. By the way my GP is very aware & supportive of this particular site and the advice given.