Hope this isn’t a naive question but is it possible to have a PMR flare without raised ESR or CRP levels?
I was diagnosed two and a half years ago and started on 10 mg Prednisolone, which helped a lot and I was able to lead an almost normal life (apart from the running and hill-walking). I gradually reduced to 5 mg and was feeling fine, but following travel injections (about which I posted) I increased the dose to 6 mg before an active holiday in Madagascar. I coped well while away (taking rests when needed) but after a 36 hour journey home (flight delays, missed connections) and then 2 weeks of visitors (arranged when I was feeling well) I have felt achey everywhere (not just shoulders and hips) and have extreme fatigue. I increased my Prednisolone to 7 mgs and saw my GP who said it was a flare, arranged an FBC, and erred on the side of caution and also checked for malaria. All results were normal, although I noted that ESR and CRP had not been requested. The only abnormality was a raised neutrophil count. A second blood test again showed raised neutrophils, still no ESR or CRP requested. This last week I returned for a final blood test. Still no ESR or CRP requested so asked the nurse if she could do this which she kindly agreed to do. Results are all normal, including ESR and CRP, except for a still raised neutrophil count. I have not felt any benefit from the 7 mgs of Pred but my GP says to stick with this dose.
I feel much worse than when first diagnosed. Fatigue to the point of trembling if I attempt too much (which isn’t actually much at all) and very foggy brained. One example of fatigue - went shopping with my sister. After 2 hours and 2 coffee breaks I had to lie on the back seat of the car in the car park until I felt well enough to drive home.
Sorry for rambling but I would very much appreciate some advice, thoughts or reassurance from you lovely knowledgable people.