I would really appreciate some advice, please. I was on 15 mg of Prednisolone when first diagnosed last September. I then tapered to 12.5 mg which was controlling the pain, then Dr Hughes told me to reduce to 10 mg, which I did, but the pain came back with a vengeance so I went to see him and he told me to go back up to 12.5 mg for 2 weeks (he also gave me an injection) and then taper down to 10 mg again for 4 weeks until I see him next. I reduced to the 10 mg on Tuesday of this week as instructed but for the last couple of days have been in pain again - my muscles are burning and my joints aching. It was so bad at 4.00 am today that I didn't know what to do with myself so I got up, had something to eat and took the 10 mg - no relief from the pain. When my husband got up he found me in tears on the sofa. He suggested I take an extra 2.5 mg, which I did, but it has not helped with the pain. My questions are - if I continue to take the higher dose of 12.5 mg how long should it be before it kicks in, and also should I actually keep taking the 12.5 mg or try again to go down to 10 mg - if so after how long? Any advice much appreciated.