i was put on Methotrexate in addition to my prednisone but just two months ago so the jury is still out on how much it will help. will keep you updated. one thing I have found out is that this GCA and PMR dance is an inexact science. i am not sure they completely know what they are doing. Sad to say....but of course....it is basically a women's disease and we don't get the research, at least in the US, that the men do. i have found out more on this website.....from all of you...then I have ever been told by a doctor.