I met someone with pbc who had been privately seeing the top specialist in this area in I think he was from Cambridge. He had been advised to keep up his levels of Vit D by skin exposure to the sun. He was told to try and get at least 1/2 hour of sun on as much skin as possible at midday without sun creams etc. He has found that if he gets enough then the itch goes. so he now goes for winter breaks to help. I have always had a winter holiday and find that it keeps the itch at bay. I am in need of some sun again to top up the Vit D so lets hope we get some soon! Hope this helps.