I am just starting a new drug trial ,Colchicine and Methotrexate plus Folate to settle side effects (has anyone tried these?)This is sort of a last ditch effort as i am not responding to all other tried and tested drugs. I also take Urso. Prednisone is for a lung disease i cant shake called B.O.O.P, anyone out there have this as a secondary disease? i have G.A.V.E (watermelon stomach) and get regular iron infusions. my fatigue is like everyone elses i guess and i try to just keep going till i cant anymore, then i sleep sitting up HA HA HA at 43 yrs of age thats funny really. i work full time in my own salon which is getting harder to do but im trying my best. i have 3 children and a supportive hubby. i have also got Hypa Pigmentation due to PBC and although i have always had a deep olive tone but i am so dark now that i could pass as an indian ??? anyone else have that?looking forward to reading your input, Snoozy
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