I have been on Imuran 50mg for over 3 years and will be on it another 2 for autoimmune hepatitis. I also have PBC and take ursodiol for that. Imuran has lowered my liver levels and has kept them stable for me. It suppresses your immune system but it’s manageable. My dr is hoping that after being on it for 5 years it will put me in remission because that is what the studies and data have shown. I initially had to go on steroids to lower liver levels and then started the Imuran. Steroids were terrible and I dread the day I have to go back on them.
Hope this info helps you. Let me know if you have any other questions.