My new doctor ran extensive tests for my sudden muscle leg spasms that got real stiff last 2 months n severe weakness. I had a negative biopsy 6 years ago. I was told my second ama m2 test was high positive at 90. He prescribed urso. I get dizzy easily and am scared of side effects. I would not take it if i didnt have such weakness n liver n digestive discomfort. I am super sensitive to meds. I doubt my new doctor, but with my family with pbc history with sis n my lifelong bouts of digestive issues n chronic pain, I have to wonder if he is right. I dont take any meds except topical acyclovir. Any advice? Hepatologist is in the works.