Low platelets? Anyone what does it mean and what happens now?
Low platelets: Low platelets? Anyone what... - PBC Foundation
Low platelets
With PBC my platelets have always been low. Just part of the PBC game!
means lowers ability if blood to clot ... thinner blood, easier bruising and longer to stop n scab is my understanding of it. if u have ANY type of surgical procedure, even teeth out, make sure whomever knows about it and yr blood type ...🤔🤗😇😁
Hi Flora
Most people with PBC will not have thrombocytopaenia ( ie low platelets). It is very much a sign of advanced liver disease and generally associated with cirrhosis.
The pathophysiology of thrombocytopaenia has long been associated with an enlarged spleen. Portal hypertension may cause the spleen to enlarge and retain white blood cells and platelets, reducing the numbers of these cells and platelets in the blood. A low platelet count may be the first evidence that a person has developed cirrhosis.
The term used is sequester which I gather means to "hold on to " or "retain" - in other words, the spleen holds on to ( sequesters) platelets, leaving fewer circulating in the blood which is then reflected in a low platelet count.
I have widespread cirrhosis and my platelet count has drifted down over the last few years but is still just within the low normal range. My consultant did tell me that platelet infusions are normally reserved for those with critically low platelet counts.
Hope this helps a little.
Karaliz from Australia
Thank you for replying have been away so had no internet my doctor phoned me and said my platelets had been at 50 but after a recent blood test they have come up to 84 so he said they will check them in another month and see .I'm off work because I feel so bad there are lots of things showing up high blood pressure 166 over 100 I'm waiting for word back from liver specialist in Edinburgh. Today I'm totally wiped out and had to go back to bed but my arms and legs are tingling they are keeping me awake .