Male, 55 years, diagnosed 20 month ago, stage 3 PBC according to liver biopsy.
First year URSO only, and bilirubin etc was back to normal and itching disappeared directly.
However, alkaline phosphatase (ALP) was still way high.
Then USRO+budesonide was tested, no difference.
Last 3 month with URSO+bezafibrate. BIg improvements on ALP already after first month, and now after 3 months, ALP is normal.
If you want to read more, google on "pbc bezafibrate" and you see there are many references. Seems to be normal treatment in Japan since the 80ies.