Intrinsic factor: I have been told that... - Pernicious Anaemi...

Pernicious Anaemia Society

32,669 members24,064 posts

Intrinsic factor

mummytina profile image
3 Replies

I have been told that my intrinsic factor doesn't work and that's why I have pernicious anemia I know that the IF absorbs B12 but does it do anything else in your body, I really don't know much about any of this can anyone help?

Written by
mummytina profile image
mummytina
To view profiles and participate in discussions please or .
Read more about...
3 Replies

Hi,

IF does not do anything ells in your body but bind to B12.Pernicious anaemia

Normally, when you eat foods with vitamin B12, the vitamin combines with a protein called intrinsic factor in the stomach. The combined vitamin B12/intrinsic factor is then absorbed into the body further down the gut at the end of the small intestine. So called R binders are produced in that part of the gut and the R binders connect to IF bound B12. So if you have no IF bound B12 in the gut B12 will not be taken up . ( IF = Intrinsic factor, it is made by cells in the lining of the stomach and is needed for vitamin B12 to be absorbed, its not used for anything ells in the body.)

Perhaps read up a bit, I found it helps a lot if you understand what it means to have PA; see:

patient.co.uk/health/Anaemi...

patient.co.uk/doctor/Pernic...

cks.nhs.uk/anaemia_b12_and_...

I hope this helps,

Kind regards,

Marre.

suki65 profile image
suki65

Have you tried intermittent fasting this helps to get your intrinsic factor up and running so i am led to believe i eat from 11am -6pm every day and only have water the rest of the time . also b12 1,000ug one a day helps ,you also could get your vitamin d checked . what is your b12 level now ?

dll5602 profile image
dll5602

What does the vit D have to do with B12?

Not what you're looking for?

You may also like...

Intrinsic Factor

Does anyone know how long the test for IF takes? My GP has said if I don’t have IF I can have...
SharonH68 profile image

Intrinsic Factor

Hi, I have vitamin B12 injections every 8 weeks but started having to reduce the length of time in...

Intrinsic factor

I seem to be at a sticking point with the findings of the intrinsic factor test. This is due to the...

Intrinsic factor antibodies

So my Intrinsic Factor Antibodies test has come back as a 1. I believe this is normal or...
Jesswoozer1 profile image

Intrinsic Factor

It occurred to me that it must be possible to synthesise Intrinsic Factor as a supplement to...
Orchard33 profile image

Moderation team

See all
Gambit62 profile image
Gambit62Administrator
Foggyme profile image
FoggymeAdministrator
taka profile image
takaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.