For those who like a dense medical read: patents.google.com/patent/W...
My take away is Nestlé is applying for a patent for a formulation of adenosylcobalamin to treat mitochondrial dysfunction and symptoms related to adenosylcobalamin deficiency which plays a role in the Krebs cycle ( energy production) . It sound like they are developing a probiotic that will make adenosylcobalamin in the body.
I have found it difficult to find studies and information about isolated adenosylcobalamin so I found this very interesting.
Many studies are summarized in the patent application that compare methylcobalamin effect to adenosylcobalamin.
I read someone's post on this form about adenosylcobalamin which is what prompted my research. Many of my PA symptoms are gone but I'm still left with exhaustion that comes on like a freight train but then goes away for a while, along with some other symptoms which may or may not be related. Could be hashimoto or perimenopause, not sure. Working with my doc but all other blood work looks good. My worst symptoms of PA have resolved.
I've only received methylcobalamin injections. I believe I've had life long PA but only got dx 2 years ago. Makes me believe I've likely never absorbed adenosylcobalamin in my life which may explain the extreme exhaustion. Or like I said, could be something else. I'm no doc but makes sense. Nice to find some info on the topic.
Hope you find it interesting as well and if anyone has any research specifically about adenosylcobalamin please share. Thanks!