I treat my polyneuropathy with B6 and B12.
GracePV shared their experience with B6, B12 nd B1. This inspired me to revisit my self treatment of my polyneuropathy.
I came across information about Benfotiamine which is similar to Thiamine Hydrochloride and Thiamine Nitrate. There are indications that it is more readily absorbed at the cellular level as evidenced by testing in a laboratory.
It is a new form and some randomized trials were actually done on humans and different doses used and even measured effects in 6 weeks rather than use it takes time if ever method. What a novel concept. : (
I will be doing a trial of 325 mg twice a day for 6 weeks oral as part of the way a 'normal' body processes Benfotiamine is in the digestive system. If that does not have an effect I will study injections of Benfotiamine and or Thiamine.
This information comes from the study of neuropathy experienced by diabetics. Those that study diabetes are of a higher quality that those that study B12. I no longer buy into it is a matter of funding because I find that would unlikely result in higher quality work. A government/nonprofit excuse for poor quality work. The solution is not always more money although that can result in higher quality work it may not and most often does not in the government/non profit sector.
A review of my work indicated that when I was taking a multi supplement it MAY have had a positive effect on my polyneuropathy and Thiamine was included in the multi supplements trials I tried. 6 months ago I stopped all supplements other than B12 and B6 as a way to isolate the effects of my supplements. I do not use the find what works method to achieve results.
I did note that science led the researchers to 300mg twice a day and the RDA is 1.1mg/day. Those that study/lead B12 treatment apparently did not note this science. The RDA of B12 is 2.4 per day so 1 mg every other day should be fine and those that lead will never feel a thing. The RDA should not be used other than RDA. Go figure.
I am aware you can not compare one compound to another linerialy. It should have led to testing and has not.