I was reading a post about an Etsy shop offering injectable B12 doses so I decided to research where B12 is manufactured. I found this really interesting site and thought others might also find it interesting. quadram.ac.uk/case_studies/...
According to the article 90 percent of B12 is manufactured in China.
yep! Some good details in that article. I posted about this new process last month:
I’m wondering why , on the photo illustrating foods that contain B12 i.e. meat , fish , dairy products and eggs , mushrooms and some grains that look a bit like oats have been included . No grains or mushrooms contain b12 that is useable .
That is a good question. Maybe they just used a stock photo and didn't pay attention.
Possible , but” B12 “ was displayed very prominently in the centre of the photo —Misleading I thought, with a scientific article .
It is possible to grow Shiitake mushrooms to contain non-analogue human bioactive B12 but I've never seen them in a store.
ref: monaghan.eu/products/natura...
I have not seen conclusive evidence that they would contain consistent enough levels of B12 to prevent deficiency, my understanding is the levels are low and variable (if they exist at all).
some research: sciencedirect.com/science/a...
However oral B12 supplements containing low doses of B12 that have been concentrated from Shiitake mushroom extracts are already on the market and you might even see them in your local supplement store. I have come across these:
bodykind.com/supplements-c1...
However, I'm not sure what's going with the food that looks like rolled oats. Maybe they were trying to represent B12-fortified cereal products but they look more like raw rolled oats/porridge flakes to me.
According to this article, long-term exposure to cobalt is "associated with cardiovascular problems, thyroid dysfunction, neurological issues and renal impairment" -
....yet any of these problems can and do apply to B12 deficiency - or lack of cobalt.
Surely both cannot be true .
Until more research is done regarding comprehensive listing of B12 deficiency symptoms and associated conditions, I remain unconvinced by this statement. Arrhythmia, Grave's/Hashimoto's, nerve damage, incontinence are problems already familiar to many people on this forum.
The inappropriate photo, as wedgewood has pointed out, just adds to my feeling that there is more work required in presenting their case. A full understanding of the effects of B12 deficiency on real people being an essential requirement.
Quite happy to be wrong on this.
haven't read the article, don't want to risk rage fest, but sounds like validity of their opinions is somewhat flawed. When stats and results are picked to support their hypothesis or at very least lazy scrutiny of information. I always feel the there seems to be real confusion about what is a symptom or effect deficiency . Dr's seem to think if it's a problem then it's caused by the treatment , rather than undertreatment. Same with Thyroid, as we all know lots of symptoms overlap, Doctors gaslighting that adequate treatment is over treatment and causes heart issues yet it is low levels that impact on heart health. Waffling now but fully concur with you Cherylclaire
I thought Germany has a laboratory as well?
One of the things that I find amusing and frustrating is the search by many folks that insist on only using "natural" forms of B12, usually methyl or hydroxo. And while it is true that hydroxo is the form found in many foods, any form that is in a vial for injection is certainly not natural. The vast majority of B12 is synthesized from bacteria in a lab. So calling cyano a synthetic form and hydroxo or methyl a natural form is not accurate. If it is in a vial for injection and has come from a production facility, it is synthetic. I am not saying that is a bad thing, just that many people use a lot of time, effort, and money trying to get "natural" B12 injections when there is rarely such a thing. We all know that different forms work better for some people and some do not, but it is certainly not due to it being natural or not. But marketing your product as natural is certainly effective, even if that is misleading.
I thought Germany manufactured b12 too. I’m sure that Hevert states it’s made in Germany - unless of course as in many things now the raw material is imported and then mixed with saline at the manufacturing end point?
It's a little worrying that 90% comes from China. I hate to think of what would happen to those of us who need B12 if problems between the USA and China caused shipments to be stopped.
That’s exactly what I thought. Started investigating when Panpharma was difficult to get, and discovered it was made in Hungary originally. Now in France in think.
Hevert is as best I know made in germany and maybe pascoe also but that is for our market not mainstream pharma healthcare markets. . . . .
Yes but I wonder if they just mix the solution and put it into ampoules with b12 imported. Nothing is what it seems these days!
I am told that b12 is not a product that lends itself easily to being concentrated, diluted remixed .. . . . I read the early problems were not making cobalamin but getting it to bind to something to enable it to be used as such. . . . . As best I remeber it is made using bacteria or growing it on or in bacteria. . . . . . If my memory serves we well the reason we have cyanocobalamin is something to do with filtration which had to a point destroyed the product but when by chance aparently some was ran through an everyday carbon filter . . . same stuff in a carbon water filter the cobalamin bound itself to the cyanide molecules in the carbon bringing them with the cobalamin but making it useable/stable whatever hence Cyano in the name. . . . I never read how hydroxo is made . . . . . That is readings from over 3 years ago and all I was interested in was how it was made not where or who made it. . . . . It may explain why there are 1ml 1000ug, 1500ug 2ml 1000ug etc because not every lab will use the exact same machinery and formula's. . . . . . None are natural as has already been pointed out. . . . . . The German Labs are worth quite a bit of money and dont want any bad reputation and I doubt very much they could make a mess of cobalamin. . . . . It is after all a metal ion cobalt. . . . It is not prone to rot or turn bad .. . . . All happens it after and extended period is that is looses its potency. . . . B1 though does stink. . . . . I would doubt that much if any of our cobalamin is made in china not that I would not worry about China. . . . . We use loads of stuff made in china. . . . . The big market is not our DIY market but rather food supplements and biggest of all those are animal supplements which is massive and will account for a very large part of the quoted 90% being made in china. . . . . China of course leading the world in mass production of animal products now inc dairy. . . . . . The rest of the 90% I'd imagine is eaten up by our domestic health care markets who couldnt give a toss where the product comes from. . . . No odds what country ye live in very little of your domestic medications are made there. . . . . India is massive as is China. . . . . Good graciious the US phara industry has made ten fortunes from having it stuff manufctured in India/China and Ireland. . . . . Ye cannot just assume that what ye are getting n the local pharmacy is made at home unless ye live beside me in which case I see many items made here. . . . . The biggest brand. origonal brand of those little blue tablets everyone jokes about are made in Ireland. . . . Alwasy were . . . . . . If you get a drip hung on to you try and have a look ans see where it/the water comes from . . . . . better than 9 out of 10 will originate in Co Mayo and the recognisable name in that is Baxter especially in the renal treatments . . . .. Ireland you ask. . . . . The answer is easy . . . . . Dirty water is dificult and expensive to clean. . . . . Same with china. . . . China does not possess near enough oil etc but it has a massive reserve of minerals built up because cobalt is used for loada of things so forget about all that stuff about EV batteries, that is just a fraction of cobalt needs and that need is falling due to new tech the same as lithium prices are falling due to new tech and hence the battery prices are falling. . . . . It is not so long ago that the mental health sector used more lithium than batteries did but gradually with our phone's, laptop's, ipads and cars it overtook the pharma industry. The car industry does not want expensive stuff. . . . . The ICE legacies used every bit as much precious metals as EVs anyhow but that is a topic for a differnt club. . . . . Really if ye could put to the back of your minds where this stuff comes from. . . . . We have no control over that. . . . . Dont be buying 100% natural cause I can bet it will come from some seedy zero control lab that cant be traced somewhere ins SE Asia. . . .
Psychiatric symptoms of B12 deficiency 
Oral B12
B12 Headache
