Interesting B12 Study

[MoKayD]

An article about new B12 research newatlas.com/medical/vitami...

[Jillymo]

Interesting recent research.......thank you for posting.

[Narwhal10]

Hi MoKayD,

Thank you.

The original study was Vitamin B12 is a limiting factor for induced cellular plasticity and tissue repair in Nature (2023). This is Evidence Based Medicine.

nature.com/articles/s42255-...

I totally understand it is more complex to understand and has jargon. However, if you are attempting to discuss a topic with a Clinician and you referenced Bronwen Thomas and New Atlas, they would laugh you out of the door. Neither are credible sources.

🐳

[MoKayD in reply to Narwhal10]

Thank you, but the original study is way over my head. I hadn't planned to discuss this information with a clinician so I guess I'm safe on that point. I just thought it was interesting information and maybe others would like to read it.

[Narwhal10 in reply to MoKayD]

I appreciate that MoKayD,

We do have to be extremely careful with trolls, sock puppets, misinformation, disinformation and all that malarkey. Someone recently transferred some information they found on TikTok about a supposed Health Guru called Gary. He stated the dangers of vitamin B12.

He was a slick salesman who trained competitive athletes, CEO’s and famous people. None of them had P.A. or vitamin B12 deficiency. He would not know that a person who is unable to coordinate their body, has slurred speech and is short of breath is extremely ill and needs this life saving medication.

😘

[B12life in reply to Narwhal10]

I love seeing that the general public gets a glimpse of the information. I do like that you pointed out that whenever we take info to a clinitian that we take the medical journal.

What's funny is if the article is long, I create a summary page and summarize the info in the medical journal; then give them the full article along with it with the facts in the summary page highlighted. This way the will more likely be to read it. maybe all they read is my summary, but at least they get the info I wanted and are more likely to trust it.

If it's a doc that doesn't accept it despite it being from a medical journal, I don't care. I can't save the world, but it's like court cases, at least it's now in their head. maybe some day it will stick or something else will come along to influence them to finally agree. I may not be around by then, but it's my way of influencing best I can.

[Narwhal10 in reply to B12life]

That is perfect B12life - the summary.

I took one page of a 10 page article. Highlighted 3 words - there we go Doc. Yes, they are xenobiotics like antibiotics. He knew I was a midwife but did not know I had worked in Developing Countries.

When is the bus ? Today. Always makes me chuckle. Loads of people do not realise that herbs and spices make awesome medicines. Aspirin comes from the Willow tree and was found 3,500 years ago. 🤪

[B12again in reply to Narwhal10]

I experimented with AI to better understand medical studies. Below is a layman’s summery of the above study you linked to that I have generated through AI. What are your thoughts on it Natwhal? Is it reasonable?

“This research brought to light the significant influence of vitamin B12 on cell reprogramming, a process essential for transforming one cell type into another. Vitamin B12 played a crucial role in supporting enzymes and processes involved in this transformation. Its absence hindered proper gene regulation through histone methylation, thereby slowing down the process of cell transformation. However, when supplemented, vitamin B12 helped enhance these critical histone modifications, facilitating more efficient and effective cell transitions.

Interestingly, the study also highlighted the impact of gut microbes on this reprogramming process. Although supplementing with B12 partially countered the effects of gut microbiota depletion, it suggested a larger role for these microbes, potentially working alongside vitamin B12 in regulating inflammation, a vital aspect of cellular changes.

Moreover, the research suggested that beyond its role in cell reprogramming, vitamin B12 showed promise in aiding tissue repair, particularly in conditions like ulcerative colitis. By promoting a process called cell dedifferentiation, where cells revert to a less specialised state, vitamin B12 played a role in enhancing tissue healing. This discovery hinted at broader therapeutic applications for vitamin B12, potentially benefiting organs with limited natural regenerative abilities, such as the intestine, pancreas, kidney, and lung.

In summary, this study's findings shed light on the critical role of vitamin B12 in both cell transformation and tissue repair. This understanding could revolutionise approaches in regenerative medicine, offering new avenues for treating organ injuries and diseases more effectively.”

[Narwhal10 in reply to B12again]

This is perfect, B12again, except for one word. Sorry, I know it sounds pedantic but second paragraph, third line. The use of ‘hinted’ to ‘suggested’. This is because of languages used in different industries.

If I said to a doctor of medicine, There is a problem with a rolling hash. Their mind interprets that as ‘cannabis use’. I actually mean a ‘#’ key where I am sliding a window of data to another. It is a search algorithm.

There is Rabin–Karp algorithm (1987), Aho—Corasick algorithm (1975) and Knuth–Morris–Pratt algorithm (1977) amongst others. I also used the Brute-Force algorithm. 🤣🤓

The Rabin fingerprint SCHEME.

Bronwen Thomason’s fingerprint (the author of the article) posted by MoKayD is very different from yours and mine. There is a databank with ALL the information though. Nowadays, we use our fingerprints to access SMART hardware. The Software Engineers have been busy setting it all up and maintaining it.

* A scheme is a large-scale systematic plan or arrangement for attaining a particular object or putting a particular idea into effect.

{\displaystyle \lambda :Q\times \Sigma \to \Gamma };

🐳

[Regenallotment]

Very interesting reading thank you 🌱

[WIZARD6787]

I like the concept of improving my cells plasticity. A possible explanation for my improvement not directly related to symptoms.

[B12life]

Interesting read! thanks for publishing this!

[MrsTuft]

interesting….

[MorningMist]

It is incredible how many processes are underpinned by b12. The more I learn though the more I think there is very little chance of this becoming accepted by the medical establishment en masse any time soon. 😕 Unfortunately for us.