Vitamin b12 levels 2000 Pmol/l after b12 injection

[Oldbloke1]

Is it normal for your vitamin b12 levels to rise that much two days after b12 injection

[Nackapan]

Yes. No worries with that.

Why was it tested?

Not needed once injections start .

Levels meant to stay high.

Mine 2as dine once as 2anted folate measured and its done with b12 .

Mine was 2000 + too.

Main thing is if you start to get relief from symotons.

[Oldbloke1 in reply to Nackapan]

Thanks for the reply.

[Oldbloke1 in reply to Nackapan]

It's done to the 500's now

[FlipperTD]

Yes! Totally pointless measuring it unless it's to prove that you've had the injection!

[Oldbloke1 in reply to FlipperTD]

No, I had a routine blood test because of the tablets I take

[Nackapan in reply to Oldbloke1]

Usually not on routine bloods .If its dropped agai you may need x higher frequency of b12 injections .

Go by your symptoms

[Oldbloke1 in reply to Nackapan]

It's 514 now

[FlipperTD]

I see! Cheers.

[palmier]

Considering that 2000 pmol/L in serum corresponds to a total of only around 7 mcg in serum (5 liters of blood in a body, 55% of which is serum; 1355 g b12 /mol), and that an injection typically is 1000 mcg, it's not surprising if serum values are elevated for some time after an injection. I imagine it takes a while for all the b12 to be absorbed by cells, which is where most of the b12 in the body normally is located.

[Oldbloke1 in reply to palmier]

Thanks for the reply, it's 514 now

[Sleepybunny]

Hi,

A few links that might be useful.

PAS (Pernicious Anaemia Society)

Based in Wales, UK.

pernicious-anaemia-society....

There is a helpline number that PAS members can ring.

PAS membership is separate to membership of this forum.

PAS membership is open worldwide and you do not need a PA diagnosis to join.

pernicious-anaemia-society....

B12 Info.com

b12info.com/

B12 books I found useful

"What You Need to Know About Pernicious Anaemia and B12 Deficiency" by Martyn Hooper

Martyn Hooper is the former chair of PAS (Pernicious Anaemia Society).

"Could it Be B12?: An Epidemic of Misdiagnoses" by Sally Pacholok and JJ. Stuart (US authors)

Very comprehensive with lots of case studies.

Lots more B12 info in pinned post "Various PA/B12D resources".

[Oldbloke1]

Thank you