Age of onset of using up B12

[WIZARD6787]

I was wondering if anyone else had early onset of using up B12 prior to DX.

When I was 3.5 my father graduated from college so I can remember that day and feel it was using up my B12. At age 8 I went to the doctor with a pain in my side that I expect is part of the difficulty breathing from B12D. At age 20 I had a reaction to nitric oxide in keeping with B12D.

You all know what I was told was the problem. ME

Looking back it was after times of stress that I experienced using up my B12. Seems during the stress my body produced adrenaline until it could not any more.

What says you?

[Jillymo]

How long is a piece of string ? It's a dificult one to answer.

I was the same and also labelled with ME, then chronic fatigue and onto fibromyalgia. I have to take my autoimmune conditions into consideration but energy and stamina have failed me since an early age.

Like yourself - I still have unanswered questions but have given up on finding answer's and just cope on a daily basis. I wouldn't say my symptom's are all due to B12 they manifested as the years ticked by with my other conditions. If like me you were diagnosed with ME your system was sluggish from an early age - hence what we suffer today. 😩

[Pickle500]

Yes, I think its all mainly stress related but also linked to gut/immune health. Sleep is a great restorer of gut health and myelin sheat/nerves.

As a kid, I had alot of trouble sleeping. I grew up with stress around me and then suffered a bereavement when we lost my father. My mother told me I went into shock and was shivering for three nights. That shivering would come back over the years and may have been buried trauma coming out in my deficiency in my forties.

I drank and took drugs, Im sad to say, and they probably also affected my B12 levels. But again, I think its also about sleep levels, gut health, diet and general stress. Genetically, some people can handle these and some people can't handle them too well.

I think some people need more B12, sleep, and reduced stress than others and that's an unfortunate and non-scientifically proven thing.

Maybe one day we can be treated according to our genetic code/DNA and not have it assumes that everyone is the same.

[Sea-blue in reply to Pickle500]

love this comment Pickle. I think you’ve summed it up nicely about the DNA/ genetic code being used to treat .

[Sea-blue]

Wizard , I can pinpoint high adrenaline / B12 usage correlation in my life too.

[bookish]

It makes perfect sense. When you are stressed your body will divert energy away from your digestive system, affecting acidity of stomach, so less absorption, plus the production of hormones and neurotransmitters takes a lot of B12 - hence less supply and more demand. All of the family members that I have/had with PA or B12D got worse rapidly at times of great personal stress. I found that magnesium helped a lot more than expected (as well as active forms of B12 and folate) and later found that genetically I am predisposed to slow COMT, which is magnesium dependent. Stress also depletes magnesium, amongst others.