I was diagnosed with B12 deficiency in the spring of 2021. I was initially placed on a regimen of B12 injections appropriate for patients with blood symptoms. Eventually I read enough to discover the difference in treatment for patients with blood symptoms vs nerve symptoms, and since August of 2021 I have been injecting B12 daily. This past summer it was discovered that I needed a pacemaker and one was implanted. I feel I have benefited from those treatments, but I still generally feel crappy. Recently I went into Google Scholar, a research-database search engine, and entered the search terms "B12 endocrine". One of the articles that came up was the following:
Pernicious Anemia and Widespread Absence of Gastrointestinal Endocrine Cells in a Patient with Autoimmune Polyglandular Syndrome Type I and Malabsorption
I was at my endocrine clinic yesterday. How I wish I could have taken this artical along with me. I have emailed it my consultant.
I asked for genetic testing whilst at the clinic to be told it might not be funded by the NHS ! I found an artical to say it was and forwarded it to my consultant.
What I found interesting in the artical you posted was as I child I had both glandular issues and candidiasus. In 1976 when my hypoparathyroidism was discovered I were also found to be mal nourished despite a healthy diet
I was told by a Haematologist 3 years ago that I have Autoimmune Polyglandular Syndrome Type 3. At the time I had Hashimoto's and Pernicious Anaemia. I have since gone on to be diagnosed with Celiac disease last year and my Gastroscopy showed that I also had atrophic gastritis and I was also told that I had no intrinsic factor. This definitely confirmed the fact that I definitely had Pernicious anaemia, and my Gastroenterologist wrote that I needed B12 injections for life, and would never be able to take oral B12. Autoimmune Polyglandular Syndrome Type 3 lists Hashimoto's, Pernicious Anaemia, Celiac disease and Myasthenia Gravis
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