Hi I preload two syringes with b12 so I don’t have to do it each day. I take them daily
I store them in a drawer where there’s not much light
But ampules are dark. Does effectiveness or anything else suffer as I take the second on the second day? Thanks
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The second one will have compromised sterility. However careful you are.
Never had problems with sterility as none others have had that I’ve read online
My question was about its effectiveness
You only need a problem with sterility to occur once.
Maybe some of those who had problems are no longer able to post?
Lol ok don’t be so morbid So u may get a small skin infection if that? It literally stays u touched and protected. Not some needle in the open air
I think you are under-estimating the possible consequences.
Sepsis requiring intensive care following intramuscular injections: two case reports
ncbi.nlm.nih.gov/labs/pmc/a...
Certainly, the two cases are towards the extreme. But they are possible results. Not just a minor skin infection.
Thanks. I do under the skin They also sell preloaded shots which are open too?
preloaded syringes will have been manufactured in a sterile environment. Unfortunately our homes aren't sterile environments and once the syringe and ampoule are open there is a risk of infection as a result.
Yes with other conditions I have it’s actually arduous. Never had problems with sterility as none others have had that I’ve read online
My question was about its effectiveness but I guess they sell them preloaded too
Thanks
Am sorry you have other conditions to deal with.....they do tend to accrue as a fair few on here will know who also have to deal with mutiple conditions....lol.
I inject twice per day. I draw up each time......it takes seconds. Id rather do that then risk sepsis. On your question will the b12 deterioate. At a guess yes because its outside of its ampoule..... but all depends on how long you are storing it like that before injecting.
I have had lots of great advice on here as there are some really knowledgeable caring people who are amazing as they give their time so freely to others...... please dont be offended ......they are trying to help you. It would be remiss of them not to warn you.....if you then choose to carry on with this practise then you do so knowing you're taking a risk. Another option is to buy preloaded b12 injections.....then you wont have the bother & will be safe. Take care.
Thank u. Yes I’m of course not offended at all the helpful advise. It’s the other things and some random blame that was put on me that I replied to. But I guess it’s sorted 
Yes it may take seconds for most but I can’t move my hands or arms very often and it means some days I even skip the dose. If I took it twice a day I think I would indeed preload as there’s not much time between the two but I understand, what u said is helpful and I’ll just do what I can but it may mean on some days I won’t inject - which may make me even worse than the very rare risk of infection lol…… this isn’t smth that people think of who commented above I think…
May I ask why do u think u need it twice? Do u feel it? If u don’t take it twice how do u feel? Thanks again
I had a lot of neuropogical symptoms many went in time with the injections but some persist - in particulate tremors, incontinence which are still wth me to some degree. If I reduce to daily then the following day my tremors increase and my incontinence returns. I notice my toes go numb. This settles when I return to twice daily. So sadly not been able to reduce frequency as I hoped. Hey ho.... My guess is that I am not able to retain the b12 hence the need for high frequency.
Sorry to hear the problem with your hands. Must be very frustrating. Id definately go for preloaded if that was my problem.
Wow sorry about that. Glad b12 helps tho. I’m sure with time it will get better. U can check other deficiencies too etc
Well b12 is quite expensive as it is for daily shots already so preloaded would cost even more but thanks
Good point.....especially if you are having to balance cost of other meds etc. Been doing daily for two years, twice daily for over a year now.....so three years into treatment Am lucky my GP supplies them. At least it works & am miles better to what I was. Hope things improve for you too.
Your gp is happy to prescribe twice daily shots?
He prescribes daily (recommended by neurologist) I pay for the other injection.
The people above definitely have thought of this - you won't get any who are more thoughtful, knowledgeable and caring!
Please do not be so complacent about the risk of sepsis. It is a very real possibility.
If you can move enough to inject then it is worth drawing up freshly at the same time. If not then you obviously need a carer and should get them to do it for you.
Otherwise do two injections on your good days to compensate.
Thanks. I already laid my thoughts about the replies.
Ehysibi. For clarification, any syringes that are sold pre-loaded are produced under sterile conditions and sealed in the manufacturing process. These are for single use only.
As others have said, pre-loading syringes and saving for later use is not something we would ever recommend (the contents are no longer sterile, may become contaminated, and thus there is a potential risk of infection/sepsis.
Sorry but whatever you’ve read online (not on this forum, I hasten to add) is giving you an inappropriate and potentiality dangerous sense of ‘security’. Just because others do it doesn’t make it right. Or safe. And it is precisely those kind of views that damage the cause of those who advocate for B12 injections to be made available OTC (underpins and confirms most admirably some medical opinions that patients can’t be trusted to do their own injections safely).
What you are doing (pre-loading and saving syringes that are no longer sterile) would never be advised or done by a medical professional (this is precisely why the ampoules are marked ‘for single-use only’).
This is a safeguarding issue - as members have kindly taken the time to point out to you.
This is nothing to do with what you call ‘being morbid’ and is certainly no laughing matter! You may not appreciate the responses left for you, but I applaud and thank those who have given you appropriate and wise advise.
I don’t appreciate you saying things on my behalf. I didn’t say I didn’t appreciate the replies did I? I engaged in conversation and even liked a reply. Then I asked about preloaded ones which u explained about. Now clear. It’s also not great for u to make me asking a question (and not carrying a banner advocating everyone to do it) whether it was ok to do it responsible for Anyone not making it OTC. That’s their own ignorance n nothing to do with me. Even other meds OTC can be misused so your point makes no sense. Thanks for contributing however. The issue was already solved above.
Nobody had a ‘view’. Someone had a question. It was answered. Thankfully without reading too much into what I said as u did.
Thank you for this careful, sensible reply.I'm sorry to see the response you got.
There’s no need for u to get into this conversation and take sides is there? And now u did, I have to tell u that, no, the reply isn’t careful and sensible. It’s blaming me for ridiculous things, and putting words in my mouth which is what’s clear and u can see that too. So no need to be a cheerleader on nothing for this ok? Thanks. The other replies are sensible, not this one clearly.
Thank you deniseinmilden. Much appreciated x
You made the argument that you’d read online that others had no problems saving drawn up (non-sterile) B12 for later use - and used this to demonstrate your belief that it was therefore safe for you to do so to.
This is a red flag issue in terms of safeguarding posters and forum members - hence my response.
Yes I said that in the beginning of the conversation as I wanted to see what others thought and what’s the correct situation. Then I discussed it further with the kind people above and resolved it for my own self (again; anyone can do what they wish). Then u put your own conclusions, words and intentions in my mouth.
Sorry for even asking this…..not really.
Again this conversation was finished above. Thanks.
exposure to any light will cause some deterioration - how much depends on how much light and for what time.
Hello! I will share a little of my experience that you may find helpful. I self inject multi-use vial hydroxo and since it’s packaged for clinic use, the insert doesn’t include proper handling instructions for an individual. For 3-4 years, I was using the entire 30ml vial and not refrigerating it over a period of several months not knowing any better. To complicate matters, frequency of injections was also reduced. I was symptomatic but didn’t really understand it because I felt so much better than I had—I thought this was my new normal.
Over a year ago, a new pharmacist realized I wasn’t filling my rx every 30 days and advised that the vial has to be replaced every 28 days and once it’s opened, it must be refrigerated. I realized how lucky I was that I had never gotten a bacterial infection from an unrefrigerated vial that I had been using for several months but I also realized that the potency had to have been clearly compromised. Is that why I had developed a full blown phobia?
I opened a new vial and injected two injections a week apart and after about 11 days, I started to begin improving. I made progress quickly but symptoms didn’t fully resolve until I went back to weekly injections.
Now, I wrap vials in aluminum foil and store refrigerated whether opened or unopened in an effort to keep the hydroxo as stable as possible.
A few months ago, I was stretching out using the vial by two weeks because there was a shortage of hydroxo and I couldn’t obtain it. Even extending refrigerated vial use by a couple of weeks caused symptoms to reappear.
I personally wouldn’t take any chances and am super careful now. Another thing to consider: a multi-use vial would contain preservatives and that may have prevented me from getting sick but single use ampules from what I understand wouldn’t contain preservatives so that might be more risky unrefrigerated. Hope this helps!
Thanks for this. It’s of course a completely different scenario but thanks for sharing. And glad nothing happened to u. U may wanna look into single use ones. Much better.
Just don't do it! It's not safe to. The effectiveness is irrelevant.
Already saw your comment below. Thanks.
Don't. Just don't. It's a bad idea. The risks are simply not worth it, however careful you are, or think you are. Don't. Did I say 'Don't do it?' Well, don't.
Sorry, what did u say? Do or don’t? :/
Ehysibi. FlipperTD quite clearly advised No! Do not save and inject the now non-sterile vitamin B12.
As your replies are becoming increasingly argumentative and unpleasant (and reported by forum members) and your questions have been answered, I am closing this post to further replies.
Whether you choose to accept and follow the advice given here is, as you say, entirely up to you. I would sincerely advise that for your own safety, you do so.
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Flu shot
Vitaminb12 shots
loading shots
Loading shots and worse hand issues
B12 SHOT. TO FRIDGE OR NOT TO FRIDGE, THAT IS THE QUESTION!!
