Hi I have been having B12 injections for the last 7 years.For the past 3 years I have needed them more often so I have been having injections every 6 weeks.
I have had a lot of stomach problems lately and recently had an ultrasound on my abdomen.It showed I had scarring on my liver.This shocked me as I am not an alcoholic!! I was told there are many other reasons for the scarring.
My question is could the B12 injections caused it.
😧
I'm not aware of anything that would mean B12 was the cause. B12 levels can be raised because of liver problems because the liver dumps its stores of B12 so high serum B12 an be used as an indicator of liver problems but it isn't the cause of the liver problems.
That is why the term NAFLD - non-alcoholic fatty liver disease - for example! No-one should assume alcohol as a cause of any liver disease until demonstrated to be the case.
And this is one possibility of a cause for NAFLD though whether your scarring is caused by NAFLD or something else needs to be shown.
J Clin Med. 2021 Jun 29;10(13):2907.
doi: 10.3390/jcm10132907.
TSH Levels as an Independent Risk Factor for NAFLD and Liver Fibrosis in the General Population
Alba Martínez-Escudé 1 2 , Guillem Pera 1 3 , Anna Costa-Garrido 1 4 , Lluís Rodríguez 1 5 , Ingrid Arteaga 1 6 , Carmen Expósito-Martínez 1 7 , Pere Torán-Monserrat 1 3 , Llorenç Caballería 1 3
Affiliations
• PMID: 34209831
• DOI: 10.3390/jcm10132907
Abstract
Thyroid hormones may be a risk factor for the development of non-alcoholic fatty liver disease (NAFLD) and its progression to liver fibrosis. The aim of this study is to investigate the relationship between thyroid stimulating hormone (TSH) levels, NAFLD, and liver fibrosis in the general population. A descriptive cross-sectional study was performed in subjects aged 18-75 years randomly selected from primary care centers between 2012 and 2016. Each subject underwent clinical evaluation, physical examination, blood tests and transient elastography. Descriptive and multivariate logistic regression analyses were used to identify factors associated with NAFLD and fibrosis. We included 2452 subjects (54 ± 12 years; 61% female). Subjects with TSH ≥ 2.5 μIU/mL were significantly associated with obesity, atherogenic dyslipidemia, metabolic syndrome (MetS), hypertransaminasemia and altered cholesterol and triglycerides. The prevalence of NAFLD and liver fibrosis was significantly higher in subjects with TSH ≥ 2.5 (μIU/mL). We found a 1.5 times increased risk of NAFLD, 1.8 and 2.3 times increased risk of liver fibrosis for cut-off points of ≥8.0 kPa and ≥9.2 kPa, respectively, in subjects with TSH ≥ 2.5 μIU/mL compared with TSH < 2.5 μIU/mL (control group), independent of the presence of MetS. These findings remained significant when stratifying TSH, with values ≥ 10 μIU/mL.
Keywords: liver fibrosis; metabolic syndrome; non-alcoholic fatty liver disease; obesity; thyroid function; thyroid stimulating hormone; transient elastography.
pubmed.ncbi.nlm.nih.gov/342...
Full paper freely available here:
I also have scarring on my liver and also informed I have NAFLD (I occasionally have a drink for celebration, but mainly tea-total lol). However, I am assuming this is down to having my Appendix and Gall Stones/bladder removed 10 years prior to me being diagnosed with PA! So I don't think it's the B12 that is doing the scarring. If you are concerned speak to your gp or ask Consultant at the hospital to give you more details. 😀
More than likely your liver caused your B12 deficiency. You just didn't realize it. Certain liver enzymes are responsible for digesting and using B12. When they are not functional you cannot absorb it.
As for the scarring, there are some disease processes, even viruses that can cause that. Alcohol isn't the only thing that causes liver scarring.
How does it feel to have too much B12?
seeing neurologist, advice on b12 injections welcomed…
