B12 symptoms/fluticasone

[Chris5629]

Question:

I’ve been recovering from b12 deficiency since February 2019. Probably 3-4 years or more of being deficient. Seemed like I was doing better. Have itchy feeling on skin since Aug 2019- don’t know if it’s allergies or nerve problems. Anxiety had gone. Now-anxiety and stomach issues are back.

Was diagnosed in October with sinusitis and prescribed amoxicillin. Stomach issues started in November. I did try probiotics but didn’t help

I have asthma and use Albuterol. I was given fluticasone nasal spray in February. Could the spray be causing my b12 symptoms to come back? Last blood test was December 2020 and my b12 was over 2000. I was told to take b12 tablets twice a week since it was so high.

I’ve had a lot of stress. Don’t know if that’s it. Seems like my symptoms are coming back.

[Nackapan]

So injections were stopped?My b12 is always over 2000

It's been done twice as done with folate by the labs.

I imagine you need your injections back.

[Chris5629 in reply to Nackapan]

I never had injections. I was told to take b12 vitamins. I did. I found I was improving. Things/symptoms went away. I did start and still have an itchy sensation that hits all over my body ( scalp, hands, arms and legs) That started September 2019. Doctors don’t care.

[cgregg718]

Interesting you ask that, in 2005 I was on fluticasone, Albuterol, and Advair at a time that My stomach problems increased (leaky gut) and B 12 drop drastically. This is when I started getting my monthly B12 shots. The pernicious anemia was affecting me drastically neurologically, it affected my speech in hand writing. Once I got my B12 shot I was a new person. I did not correlate the steroids to the B12 deficiency but it certainly could cause a lot of other problems for me like anxiety.

[Chris5629 in reply to cgregg718]

I was just told to take vitamins. It’s really annoying and irritating. Everything went away/improved in 2019. In September 19, I did start getting itchy feelings from my scalp, hands, arms and legs. Doctors won’t help. Now it’s all coming back including the fatigue. It’s really annoying.

[VellBlue]

Hi Chris,

There's a thread on here about amoxicillin. May be interesting to read.

healthunlocked.com/pasoc/po...

Also, if the B12 supplements were helping, given your symptoms are returning, I'd suggest taking it more often than just twice a week. You can't take too much B12. Many who have had long term deficiency need to take quite a lot, just because blood results say over 2000, it doesn't mean you are getting enough to mitigate the damage of the deficiency, go by the symptoms.

[Cherylclaire Forum Support]

I have recently been given nasal spray, which is fluticasone propionate (a cortico-steroid), and feel as if it is affecting my B12, so looked it up.

I can't find much, aside from St Luke's having fluticasone listed as depleting B12. Also topical corticosteroids on a list of drugs that deplete B12 from University of Maryland medical center. Amoxycillin and many other antibiotics included on this list too. Worth a look.

I found that when at my worst, I was susceptible to infections and it was difficult to get rid of them. I was given Doxycycline (for possible SIBO) and later Metronidazole (for gum infections), both of which gave me the same adverse reaction: constant vertigo and headache. Years later, after improvements, antibiotics did not seem to affect me so badly.

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