Does b12 irritate your bladder?

[CW12]

I have pernicious anemia and interstitial cystitis. Recently I have been having a flare of frequent urinating and pressure. Has any not had a similar issue. Do you think it’s related to my weekly injections?

[lesbud1]

you certainly pee out the excess of vitamin B12 as it is water soluble but whether it causes pressure I would be dubious. it may be you feeling your bladder getting full?

[Nackapan]

Perhaps drink more water and see if that helps. Barley water is helpful.

The colour will be different with all the supplements you are on.

I dont know but I woyldnt have thought b12 would affect your condition. If in doubt the nurse hopefully will know.

[CW12 in reply to Nackapan]

Yes and coincidentally I did slow down with water. Trying to drink more. Thank you

[rainbow4321]

I have IC, too, and I wondered the same thing. I sometimes take oral B12 (methylcobalamin) and sometimes it does seem to cause an IC flare-up. But I'm not 100% sure. From what I read online, it's not supposed to do that, but who knows.

[CW12 in reply to rainbow4321]

Interesting I was told that it could be a bladder irritant and saw some articles online that said the same. Not easy having pernicious anemia and IC

[rainbow4321 in reply to CW12]

Nope, I bet it isn't. I don't have pernicious anemia, but I am always low on B12 and I have a lot of chronic health problems including several autoimmune diseases. So I am in a similar boat as you are. And, yeah, it is NOT easy.