Parietal cells can be damaged in pernicious anemia. These cells produce hydrochloric acid necessary for digestion of proteins. So I wonder if pernicious anemia could lead to some degree of protein/amino acid deficiency because of digestive problems, and if some of the symptoms people have could be related to this.
Pernicious anemia and protein deficie... - Pernicious Anaemi...
Pernicious anemia and protein deficiency?
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In the modern diet there is plenty of protein. The achlorhydria caused by PA might reduce the absorption of proteins, but not stop it totally.
The symptoms of a severe protein deficiency (kwashiorkor) don't resemble those of PA to any real extent.
It would make sense if HCL is necessary for digesting protein. I am susceptible to iron deficiency for what I understand is a similar reason - stomach acid is necessary to absorb iron. I take Betain Hydrochloride supplements - a stomach acid replacement in capsule form which is readily available from ebay/Amazon and may help.
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