Adverse reactions to b12 injection therapy?

[Shajarin]

I'm probably deficient in b12 as I have many of the relevant symptoms (including neurological) so I started b12 injection therapy in the advice of my Doctor. I'm using cianocoblamin 1000 mcg injection each alternate day until I would see an improvement.

One of the scariest symptoms I have now is heat wave in my right leg from the lower right back to the whole leg - I feel this on and off for couple of days. It used to happen before the therapy but only in the right lower back and at lower level of severity. The Doc doesn't know what it is (no disc issues found) and he says it could be an inflamed sciatic nerve. Could it happen as a result of my b12 injections? as part of some blood plot over there? Or maybe one of the shots I had at the right upper bottom (certainly in the muscle far from the nerve line) caused an inflammation that got somehow to my nerve?

Also, After 5 injections I noticed that my skin became dryer, reddish with tiny dots or red lines (no hives) in certain areas in my body (parts in hands and hips) and those in hands were itchy a bit (not much). It started just after the fifth injection and took place mostly after hot showers and run for an hour or two and then disappears. The weather in my country is a bit colder than usual and very dry so maybe it is because of that? I'm also mildly deficient with iron so it could be the cause?

Should I need to afraid from b12 allergy? start reducing the frequency of the shots? or continuing therapy as usual?

[clivealive Forum Support]

Hi Shajarin if you've had the "heat wave" symptoms before the B12 injections started these are unlikely to be the cause of those you are having now.

As for the "tiny dots" a wiser person than I has written previously:

"The pimples/acne, is likely to be caused by microbes on your skin reacting to the additional B12 by producing substances that your skin is then reacting to. In theory this could be resolved by use of a good skin wash. You might have better luck talking to your pharmacist and seeing what they can recommend prior to your next maintenance shot - though there is always a chance that it was something that won't recur".

I am not a medically trained person but have been having cyanocobamalin injections every month for over 47 years due to P.A.

I wish you well

[gingerbear644]

The side effects I get from the Cynanocobalamin is horrible pains in my hands and feet. The same glove and sock syndrome as if I am deficient except it is not pins and needles but rather severe pain. Cessation of the drug reverses the effect.

So I alternate between Neurobine IM (mixture of Cynanocobalamin, B1, B6 since the combo is better for nerve healing) and Methylcobalamin. You need to monitor your symptoms. The doctors regrettable can't tell you how u feel and many can't treat so you need to do your research to find out if others suffer from it.

Just letting you know there are side effects. You need your B12 shots but its possible you may need to change the type.

[aksundell]

I have had the warm flushed feeling in my hands and feet after starting b12 for my neuropathy. I have been thinking of it as a sign of healing. Strangely the right side of my body improved within 2-3 weeks of starting b12, but my left side, which was slightly worse to start with and is my dominant side, initially got better for the first 3 weeks and then got worse before it started to get better. In fact I have symptoms now, 2.5 years into treatment that I didn’t have when I started, but overall I’m doing better and continuing to improve. I think sometimes healing is difficult. I suspect there is a lot of remodeling going on in my nervous system which takes slot of energy and resources and sometimes things are torn down and not rebuilt yet.

I would recommend you continue every other day injections not just until you see improvement, but until improvement has stopped. Also pay attention if exercise makes your symptoms worse you may have to limit or pace your activity while your body is working overtime to fix the damage that has been done. I wish you a speedy recovery.