b12 strange symptom

[sigo]

Hello, I am new here. English is not my native language, so please excuse any mistakes... I have been vegetarian since 2013 and long period I had excellent health until a lot of symptoms started in January this year. I have been to many doctors and everybody said that everything looks fine even the following: b12 221 (142-725), homocysteine 12.2 (<15), D 55,4 (>50), hemoglobin 177 (120-180).

I had next symptoms: spasm in chest (at first I think something is wrong with my heart), smaller spasms in other muscles, formication all over my body (on the tonque also), fasciculations all over, pins and needles all over, pulsatile tinnitus, dry skin, mood changes, heart palpitations, electric shock sensations, problem with ED, constipation, problems with sleeping (short sleeping and do not feel refreshed in morning) and many others. I think palpitations and tinitus hapenned after injection, and many symptoms later disappeared or reduced significantly, but still for me is terrible only one symptom which I will describe,

I started hydroxocobalamin injections (OHB12 2500 mcg). A couple of hours after 4th injections I felt something like short "explosion" (painless) in my thights. Next days I touched thights with fingers and noticed that the tissue between upper layer of skin and muscles is cracked. I stoped injections for 15 days and check b12 in laboratory, this time it was >1476, above the limit which instrument can measure. However, I started injections again because the some of symptoms did not improve, and couple of hours after 5th injections again the same feeling but now above the bladder (connective tissue between skin and muscles is cracked or splitted and looks like grid).

That is the worst symptom and I think maybe can not be improved. Now I have cracked and damaged layer under upper layer of skin all over my body, and visible pulsations of arteries on head, arms, neck, legs, stomach because layer where they lie is wasting...

I did not find anything abouth this symptom on Internet, unlike others that have a clear correlation with vitamin b12. Many symptoms disappeared but this one not (superficial tissue wasting). Can this be side effect of OHB12 injections, or maybe that is consequence of b12 deficiency??? Last week I had pain (neurogical, like burning) in tonque and in lower lips and after two injections pain dissapeared. Fasciculations start again these days and I am not sure should I receive injections again (I also tried b12 pills before and did not notice improvement after supplementation). I would be grateful if anybody can help or give any information.

[Statesideheather]

I am not a healthcare provider so my comment is not a professional opinion.

I do not know what all could be the cause of what you are experiencing BUT I can say, from my experience, that nerve healing and other healing due to B12 deficiency does cause strange sensations and feelings. Even if you are deficient and in a state of healing, your B12 blood levels will test high due to supplementation.

I can say that I've experienced the symptoms you've listed (minus the ED because I'm a girl), and they all seem to have been due to B12 deficiency as they've all improved over time with supplementation. However, even with the improvement and regular injections continuing, I will experience odd symptoms. They are less severe and shorter in duration than before. But they are reminders that I need to continue with regular injections .

I hope this helps! Good luck 😊

Oh, it may help to try another form of B12. I do not feel well with Methylcobalamin. It makes me feel anxious and not well. Hydroxocobalamin was not as bad but after several months I really noticed the side effects. I do really well with the cyanocobalamin. No idea why. We are all different. It may be worth trying another form of B12 though!

[sigo in reply to Statesideheather]

Thank you for reply. I also think so, that many symptoms improved after injections, but this one with superficial tissue is problem. This really confused me, do not have idea is it consequence of defficiency or overdose.

Fasciculations and nerve pain started again these days, several months it was ok, and maybe I will start injections again to heal this. In my country I find only ohb12 injections, methylcobalamin pills and cyanocobalamin pills.

After pills I have not noticed any improvement, only colored and smelly urine. I will try adenosylcobalamine, I can see it can be ordered from another country.

[Bluebears2]

I am not sure how long you have been having your injections or how frequently you are receiving them. You might be experiencing the Reversing syndrome where some symptoms are elevated for a short while following your injections. Also what cofactors are you taking? You need to be taking these along with your injections daily. You also need to have high potassium foods pre and post injections. ( I have a banana/coconut water and coconut milk smoothie). Hope you find some relief soon.

[sigo in reply to Bluebears2]

Thank you for reply. Yes, I know for potassium. I was taking methylcobalamin and cyanocobalamin (300 pills, 200 m and 100 c) and maybe did not help too much in my case (neurogical problems) because only small amount is apsorbed.

I have received approximately 20 injections, 4 in the begining for four days in a row (2500 mcg), and others sometimes 1, 2 or 3 every month (1000-2000mcg).

Doctors did not beleive me for symptoms (I am only 26), and refuse to give injections, so I am giving myself injections.

[Ryaan]

2500mcg ?......Is that a 2.5ml injection as a single dose ?

The normal injection is 1ml

If you’ve been injecting 2.5ml that is too much and may well be the cause of your problems.

[sigo in reply to Ryaan]

Sorry for the late reply. One ampoule contain 10 ml of dilution and 2,500 micrograms of b12. In the begining I used full dose but later approximatively about a half of ampoule.

[Hidden]

Hallo,

The symptoms of B12 deficiency are with a great variety, because we are all different. I think OHB 2500 is from Serbia. You can try Articlox, going to Greece - 1 mg in 2 ml. Hydroxocobalamin. I have peripheral neuropathy from 4 years, I feel no difference injecting Cyano, Hydroxo or Methylcobalamin. Also try with Folate and Magnesium. I self inject 3 times a week, now I feel much better. I am not medically trained.

Be happy and don't desperate.

[sigo]

Thank you for your advice. Yes, it is from Serbia and helped me for recover normaI functions, but I am not sure about one thing which I described. That is probably the key to combine different b12 forms with certain vitamins and minerals for optimal results....