Just noticed I'm developing some slight numbness in my right thumb which has been consistent along with some occasional tingling/nerve pain in the feet. I'm also still weak in the legs. After being b12 deficient for 10 years and after my low b12 diagnosis (159), I've been on heavily supplements with an initial loading dose of injections every other day for a month followed by a 2 a week since then for the past 3.5 months. I also take oral and sublingual b12. I take both cyano and methyl/adeno. Just noticed the numbers in my right thumb today and just cant understand where it's coming from. Folate, thyroid perfectly normal. I'm going for another blood test on Monday to check my folate, homocysteine and for anemia. Hoping for some positive news. I need it.
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lownskater52
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It might go ad quickly as it came. I get numb feet and tingles in feet legs ans hands . Not painful though so do a littke pysio . Often injections s bring out symptoms as part of the process of healing. . Good to get your bloods done. Are you keeping notes on symptoms? I find it helps. Some have been there all the way through. Some gone. Some come and go. Go by your blood results what to supplement. I was throwing too much into the pan. I've cut back now trying to maintain levels. B12 is I imagine e very high still but that's what's been needed .
Hi lownskater52 I still have neurological symptoms which come and go like tinnitus, pins and needles, burning feet, pains in the hands etc. I guess it's down to nerve endings having been repaired "waking up" and signalling the brain "hey - I'm here"
Hey Nackapan. I had 1 month of injections EOD and now I'm at 2 a week. I alternate between cyanocobalamin and methylcobalamin as we dont have hydroxycobalamin here in the states. I also take 1mg oral cyanocobalamin daily.
Okay. Just keep going . We all have blips. I felt like I got stuck for a while. For me it's a very slow process . You've been very thorough in your bloods and supplements so it's rest and patience and more patience!
It might be a slight deficiency of something else is stopping your B12 working properly... Even if you were OK it maybe that you are becoming deficient as so much damage is repaired so worth trying a broad spectrum multivitamin and mineral supplement at least.
It sounds like you're probably just not getting enough B12 on 2x/week and you may need to increase your jab frequency again.
Hey Deniseinmilden. My last full vitamin work up was on June 10th which was about 1.5 months after starting b12. I had my vitamin D, A, B1, B2, B3, B6, B12, E, K, C, folate and a CBC and all of the vitamins other than b12 (2000+) and my CBC (anemic) came back perfectly normal. Thyroid also normal.
Right now, everytime I take large doses or oral b12, my feet tingle/have pin feeling pain and this time my right thumb went a little number. It's gone for the most part from yesterday but there is still some residual numbness. I guess I need to up my b12 even more. I have a blood test on Monday that will be checking my folate, homocysteine and a CBC to check on my anemia. I'm hoping for some type of good news...
Minerals are at least as important as vitamins and it is my suggestion that you are short of potassium.
This often drops when B12 becomes available to the body, from frequent injections, for repair of long-term damage as so much is needed for new cells and their functioning.
It is vital for nerve transmission (it's a main ion used to transmit the electrical pulse across the synapse from one nerve fibre to the next) and a shortage can cause numbness just because there isn't enough to go round all the new nerve fibres.
You must be careful with supplementing minerals as it is possible to have too much so I suggest that you get these tested too.
The main ones that are more likely to be a problem to you are potassium, magnesium and iron. I suggest that you Google these to find out the effects of deficiency and excess and what dietary sources you might like.
Be aware that mineral levels fluctuate quite a lot throughout the day depending on what you have eaten and how much exercise you have done but blood tests will give you a guide to your levels, especially if you manage to get them done when you are experiencing your symptoms.
Once you have had the tests you can boost your levels until you get your results back with foods high in potassium such as bananas, coconut water and nuts, particularly Brazil nuts.
In the UK we can get LoSalt and in the USA I think you can get NoSalt that is mostly potassium chlorine instead of sodium chloride which you can use to replace your table salt.
It's good to be concerned and listening to your body as it is important to get it sorted to prevent nerve damage.
I agree with deniseinmilden. You should be having b12 injections every other day until no further improvement when you have neurological symptoms -thats the nhs own guidelines. I actually need mine daily & am grateful my GP has agreed to this. If I dont have them daily my neurological sy,ptoms worsen on the second day......no idea why I need such a high frequency but daily has given me further improvement. I feel much better.
Yes we all so different in the frequency needed. Does take a long time to try and work it out. I tried stepping up but have gone back to 2 weekly at present . Like you fortunate eventually with alot of persuasion have got this flexibility with my G.p. . I don't think they know what else to do with me lol
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