severe upper back and shoulder blade pain after B12 injection

[GastritisB12]

Hello,

Has anyone else had this? I had a intramuscular hydroxocobalamin (neo cytamen) injection in the arm today, 7 hours later I have severe muscle tightness/pain spasm in the upper back and under the shoulder blades.

I had my NHS loading dose of 6 the last one of which was 3 weeks ago, today was my first private injection after symptoms started coming back.

[Gambit62 Administrator]

not something that I have experienced in relation to B12

I suspect it probably isn't related to the B12 injection.

I do find that twinges in my upper back and shoulder blades are often related to mild viral infections.

If it continues /gets worse suggest you make an appointment to see doctor/nurse.

[GastritisB12 in reply to Gambit62]

Thanks, and apologies, it seems I may have pulled a muscle trying to unlock my front door lol! Its better now. I just didn't think I had gotten that weak! To pull a shoulder muscle unlocking a door!

[Gambit62 Administrator in reply to GastritisB12]

Glad the mystery has been solved.

Unfortunately one of the things that B12 deficiency does is leave your muscles very weak. Hope that the regime for supplementing the paltry NHS regime starts to pay dividends soon

[GastritisB12 in reply to Gambit62]

I hope so too, shame that the GPs didn't want to give me more. Yes I definitely feel much weaker than normal.

Do you know by any chance how long the hydroxo injections stay in the system?

I read online somewhere that most of it is excreted in the first 72 hours?

I just don't believe when the doctors tell me the injection will keep my blood b12 high for months.

Sorry for going off-topic just wanted to get your veteran opinion.

[Gambit62 Administrator in reply to GastritisB12]

on average hydroxocobalamin lasts about 2 months in blood at before falling below the normal range - however that is an average - some people remove it through the kidneys much faster - and others much slower.

Also the normal range doesn't really apply in the same way after loading shots - these raise serum B12 levels and in some people that seems to mean that the process that allows blood to pass from blood to cell becomes much less efficient meaning that they eed to maintain much higher serum B12 levels to ensure they have enough B12 getting in to their cells. These people also seem to be much less efficient at removing B12 from their blood so serum B12 levels stay higher longer.

Basically the only way of managing things after loading shots really is to go by symptoms

[GastritisB12 in reply to Gambit62]

Thanks for the detailed response. Sounds like its very complicated what happens in there with B12 and tissue.

I just found this interesting article.

bloodjournal.org/content/18...