nerve pain and B12 injection - Pernicious Anaemi...

Pernicious Anaemia Society

32,623 members23,984 posts

nerve pain and B12 injection

Purplegirl2 profile image
5 Replies

I have neuropathy in my legs that I was born with and I get pain flares every so often. Today I noticed a particularly severe pain flare up after my subq b12 injection in the afternoon. The pain came on suddenly about 7 hours after my injection. It’s the usual leg pain I normally get - knees, upper thighs deep burning pain and tingling. I’ll have to wait and see if the pain spreads down both legs this time. I wonder is this a coincidence or should I expect more frequent b12 shots to trigger the pain more often? I never noticed a pattern of the pain increasing with my b12 shots before. My neuropathy doesn’t really have a pattern to it but I expect it’s been worse when my b12 is low.

Written by
Purplegirl2 profile image
Purplegirl2
To view profiles and participate in discussions please or .
Read more about...
5 Replies
Nackapan profile image
Nackapan

Initially I did get more pain . I expect everything waking up.

I didn't have anything going on before b12 deficiency to compare too.

I m only guessing but a surge of b12 may well try and heal nerves.

You can also hit a nerve that might set off this chain reaction when injecting too.

I do notice if I've painful legs and hips a b12 injection does help and I sleep better. 😴

Peder1962 profile image
Peder1962

It happens 40% when nerves wake up. You should continue inject often to get better. Most inject 2-3 times per week. How often do you SI?

Purplegirl2 profile image
Purplegirl2 in reply toPeder1962

i just started on an OOD injection schedule (for 1 week). I’m on my 3rd injection. Then I’ll be on 2-3 per week and then stick to 1 shot a week for the long term. My levels are low right now & I have bad fatigue and brain fog. I’m so grateful that I can self injection now. And my doc even ordered subcutaneous injections and insulin needles so it will hurt less.

Nackapan profile image
Nackapan in reply toPurplegirl2

That's good. I do sc injections at home with s 30G needle 1/2" long

Purplegirl2 profile image
Purplegirl2 in reply toNackapan

nice. That’s good that your needles are also pretty thin so it hurts less.

Not what you're looking for?

You may also like...

Burning lower legs and feet after B12 injection

Hi After my last B12 injection over a month ago I noticed my legs had a burning sensation in the...
mistygrey profile image

Feeling Worse After B12 Injection?

Hi, so I have received my 6 shots of B12. It’s the one that begins with an H (I can’t spell it). My...
Quinny99 profile image

B12 deficiency and nerve pain

Hi! Hope you are all doing well. I am a 35 year old mum of two. Started getting burning sensations...
Madirah profile image

B12 injection

Hi All Question: Is there an obvious reason why one might get a surge in ones signature symptoms...
Alfabeta profile image

What is the procedure to start B12 and to measure b12?

I am fairly new on this forum having signed up upon the diagnosis of pernicious anemia by my...
jersey-jazz profile image

Moderation team

See all
Gambit62 profile image
Gambit62Administrator
Foggyme profile image
FoggymeAdministrator
taka profile image
takaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.