Low platelet count: Hi, I haven't been... - Pernicious Anaemi...

Pernicious Anaemia Society

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Low platelet count

Sick-and-Tired profile image


I haven't been diagnosed with PA. I have hashimotos but Levothyroxine hasn't relieved the fatigue so I'm exploring what else could be doing on.

I have parietal cell antibodies, which i know can have an impact on b12 absorption (although my GP says these antibodies are meaningless). My b12 was around 330 so i started using a b12 oil and a folate supplement.

However, my main question is whether anyone knows whether the fact that my platelet count is always low is an indicator of anything?

It's not breathtakingly low, it's in the range that's below what it should be but doesn't cause a problem - always between 100 10*9/L and 130 10*9/L (range 150-450)

I found some blood test results from about 10 years ago and saw that was already a problem back then, and has been consistently below range every time I'm tested for the last 3 years.

While i know this isn't that low, and may mean absolutely nothing like the doctor says, I just wondered whether anyone would suggest it might be indicative of anything?

Thanks in advance!

4 Replies

Hi sick and tired , it may be worth you joining the ITP support Association in Health Unlocked. . Idiopathic Thrombocytopenia group . I am a member ( it’s free ) as my husband has low platelets also PA , hope it helps you get some answers . They advised me to get his blood checked regularly and to look out for unexplained bruising or bleeding such as nose or gums . Good luck .

Thanks, I'll do that!

I really appreciate your help!


I have read that there may be a link between H Pylori infection and ITP.

H pylori infection


Have you ever been tetsed for H Pylori?

H Pylori and ITP



PAS (Pernicious Anaemia Society)

Based in Wales, UK.


PAS tel no +44 (0)1656 769717 answerphone

B12 Deficiency Info website


B12 books I found useful

"What You Need to Know About Pernicious Anaemia and B12 Deficiency" by Martyn Hooper

Martyn Hooper is the chair of PAS (Pernicious Anaemia Society). Book is up to date with UK b12 guidelines.

"Living with Pernicious Anaemia and Vitamin B12 Deficiency" by Martyn Hooper

Has several case studies.

"Could it Be B12?: An Epidemic of Misdiagnoses" by Sally Pacholok and JJ. Stuart (USA authors)

Very comprehensive with lots of case studies. There is also a paediatric version of this book "Could It Be B12? Paediatric Edition: What Every Parent Needs to Know".

UK B12 documents

BSH Cobalamin and Folate Guidelines


Flowchart from BSH Cobalamin and Folate Guidelines


BMJ B12 article






I am not medically trained.

Hi, thanks so much for all this useful information (sorry for my delay responding). I did buy an h. Pylori test from blue horizon a couple of years ago but it came back negative. I have heard you can get false negatives though so maybe I'll see if I can be tested again!

Thanks again for your advice.

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