Looking for advice regarding the stor... - Pernicious Anaemi...

Pernicious Anaemia Society

32,114 members23,267 posts

Looking for advice regarding the storage of B12 ampoules....

ARRozental profile image
7 Replies

Hello.

I have ordered *100 Vitamin B12 Depot Rotexmedica and am aware that the enclosed instructions will most likely be in German, including the instructions on storage. As such, are there any special provisions that I need to make for storing the B12? Can I place it in a medicine cupboard/drawer or will it require refrigeration or a temperature controlled environment?

Thanks.

Written by
ARRozental profile image
ARRozental
To view profiles and participate in discussions please or .
Read more about...
7 Replies
ARRozental profile image
ARRozental

Also, does anyone know whether Vitamin B12 Depot Rotexmedica is methylcobalamin or hydroxocobalamin based? I am hoping that it is the latter, as I have been told that it is more effective.

wedgewood profile image
wedgewood in reply to ARRozental

Rotexmedica produce both Cynocobalamin and Hydroxocobalamin.I have just read through the leaflet that comes in the packet . At point 5 ,” How to store B12 depot-Rotexmedica “. It just says keep out of the reach of children . Do not use past the use-by date .Keep ampoules in the packet so that the ampoules are in the dark..

It also says that the contents of the ampoule should be used immediately after opening . Any unused portion should be disposed of .

Strangely no mention of keeping below 25c , or not keeping in the fridge .

There are no instructions on the packet itself

If I have the strength , I will e mail them and ask about temperatures

Gambit62 profile image
Gambit62Administrator

could be either cyano or hydroxocobalamin depending on what you ordered- they do both.

Most important thing in terms of storage is keeping away from light - second is keeping below 25C - so no need to keep refrigerated unless the room temperature is above this.

Phials are glass so don't put them in the freezer and keep them away from heat sources - latter is certainly one of the storage instructions.

deniseinmilden profile image
deniseinmilden

I Googled "Vitamin B12 Depot Rotexmedica leaflet" and got the following pdf.

medicines.org.uk/emc/files/...

It is the same as the one in the box of ampoules I had once from my Dr and I think it is for the ones you have bought.

Somewhere on here I saw that if it says "Depot" then it is hydroxocobalamin. I believe Rotexmedica also make cyanocobalamin but it is considered to be slightly shorter acting and therefore isn't called "Depot". If anyone can verify this, please, it would be good.

In hospitals and Drs surgeries they are kept in a drugs drawer or cabinet at ambient temperature and I am not aware of any extra care to try to keep them below 25 degrees.

I always keep some ampoules in my car in case I can't get home before I need my next jab and I regularly use these up. Consequently these get pretty hot at times but I haven't noticed any difference in them.

The main thing is they are kept dark (light will degrade the B12), cool, and dry (so the packaging doesn't grow moulds or bacteria which could contaminate your injection site).

Well done on getting this far and good luck with getting your life back.

You may find that you will also benefit from taking a broad spectrum multivitamin and mineral supplement plus extra folate, potassium, magnesium and iron as your body will use up extra vitamins and minerals to make the B12 work properly and help to repair damage caused by the deficiency.

shaggee profile image
shaggee

Just checked my box which was from the chemist and says store below 25 C and away from light. (Hydroxocobalamine)

Cheers

ACritical profile image
ACritical in reply to shaggee

I store mine in a Tupperware box in small fridge I keep for water and drinks in utility room. It occasionally gets opened so no regular temperature fluctuations, light off most of the time. Probably will last a bit longer then use by date that way, I hope.

ARRozental profile image
ARRozental

Thanks for your helpful replies.

You may also like...

Storage of ampoules in hot weather

(and checked their website in German) and the only usage/storage instruction is not to exceed the...

B12 storage in the liver

question on liver stores of B12. If someone has PA, do they no longer absorb B12 to their liver?

How to open B12 ampoules!

I have bought some 1ml B12 ampoules (Rotexmedica) but I have got no idea how to open them! I tried...

Where to get B12 ampoules

Hello all. I ordered Rotexmedica B12 ampoules from Bodfeld a few days ago and have had a message...

B12 100 Ampoules for €57.98

their much needed injections. I've just reordered B12 from Bodfeld Apotheke. 10 x 1mil x 10 for...