Pernicious Anaemia Society
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Continue B12 injections?

I have finally finished my B12 replacement therapy . I have checked that my B12 active level is where it should be and have been advised by a very clever doctor who may be to quite a few of you out there , that I can juice down now from a daily injection to a weekly injection and to continue healing

That's good news for me isn't it has anyone got any views on this with regards to reducing down my daily injections to once a week?

Onwards and upwards believe me this is taking a long time with no help from the NHS, MS Society , Ms Trust or Spire Healthcare

2 Replies

Hi toph are you in the U.K?

That's good to read you are getting the treatment you need.

As to the frequency of injections after "loading doses" (replacement therapy?) the U.K N.I.C.E. guidelines say that the initial dosage should "continue until there is no further improvement" in neurological symptoms and then maintenance injections of hydroxocobamalin every eight to twelve weeks.

The N.I.C.E guidelines are below. Click on the link, then on "Scenario: Management" and scroll down to "Treatment for B12 deficiency"

However this "one size fits all" regime doesn't suit everyone but fortunately, as you cannot overdose on B12 as any excess is excreted via your urine, continuation of the loading doses will do you no harm.

Have you had your Folate level tested?

I am not a medically trained person but I've had P.A. (a form of B12 deficiency) for more than 45 years.

I wish you well



keep a diary of symptoms and use those to guide when you need your next injection


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