Allergy aafter injection

[Beliverok]

I've just had my first b12 injection today and I've did my self in car on hospital parking in case 😊. I just want to ask if wasn't any allergy reaction directly after injection then I can be safe now ? Or anything still can happen? That was 10 hours ago.

[clivealive Forum Support]

Hi Beliverok some people (myself included way back in the mid 1980s) have reported B12 side effects

when hydroxocobamalin was first introduced and I came out in an awful rash.

A wiser person in this community has explained that "the pimples/acne, is likely to be caused by microbes on your skin reacting to the additional B12 by producing substances that your skin is then reacting to. In theory this could be resolved by use of a good skin wash. You might have better luck talking to your pharmacist and seeing what they can recommend prior to your next maintenance shot - though there is always a chance that it was something that won't recur."

Hopefully you will have no adverse effect from your injection. Well done for "taking a precaution" but by now I should think you are beyond having an allergic reaction.

Do you know what

your Folate level is?

I am not a medically trained person but I've had P.A. (a form of B12 deficiency) for more than 45 years.

I wish you well

.

[pvanderaa]

At the GP’s surgery, when i got my first jab, the nurse kept me for 30 minutes, to observe that I didn’t get any immediate reaction to the jab or any of its ingredients.

Start a log book and treat the jab as day 0 each cycle. Record the start and finish of any symptoms and try to assess your own severity score. The symptoms from the jab, arise usually within 3-4 days.

Next time you get your jab do it again and see what repeats. These symptoms arise from the jab and, although they may seem counterintuitive, they are “good” indication that the jab is working.

Headache, aggression, hyperactive, acne, new pain (nerves are healing) many of the same symptoms you get before your jab as your B12 depletes. It is like a roller coaster ride of ups and downs,

The higher your score, the more depleted you got before the jab and it could indicate that you need more frequent jabs.

[Foggyme Administrator]

Hi Beliverok. I suspect that the allergic reaction you're referring to is anaphlactic shock. This is a very rare (nevertheless possible) severe alergic reaction, the main danger being swelling of the lips, tongue, face, throat, difficulty breathing and irregular heartbeat). This is the reaction that would require immediate medical treatment (injection of adrenaline).

This kind of reaction would occur very quickly following injection - usually almost immediately or within five-ten minutes, so it’s very unlikely that you would have this problem after ten hours.

Anaphylactic shock is much more extreme reaction a slightly different than some of the side effects that can occur, though many people get no side effects at all from B12 injections (the main one we read of here is acne - but again, this is only experienced by some people, not all).

Here's the patient information leaflet for Hydroxocobalamin (the main cobalamin used in the UK), which lists possible side effects:

medicines.org.uk/emc/files/...

If you are taking a different form of cobalamin, input 'patient information leaflet' on the Internet, followed by the name of the form of B12 you use, and you'll find the relevant leaflet for whatever you use.

Have to say though that many of the side effects listed as being possible with B12 injections are also symptoms of B12 deficiency - and symptoms sometimes get worse when initially treated (part of the healing process) so it's often difficult to tell what’s due to healing and what's likely to be a side effect.

It's worth noting that whilst the first ever injection is the one most likely to cause anaphylaxis, this sort of extreme alergic reaction can develop at any time, so if ever affected (as per the symptoms above) medical treatment should be sought immediately - though have to say, this sort of 'late-in-treatment' reaction is very very rare. So, just something to be aware of, but not something to worry about every time you have an injection 😉

Really impressed that you placed yourself in a location where you could get medical attention quickly - but oh what a shame that so many of us have to 'go-it-alone' to get a cheap, safe, life saving vitamin.

So...finally, yes...you can ow be safe from anaphylactic shock.

Good luck and post if you need any help in the future.

👍

[Beliverok]

Clivealive,Pvanderaa,Foggyme thank you for your replies. My second shot of b12 is Monday. What I noticed after first shot is panic attacks, a little tingling of the cheek, and I fell like I came back to symptoms from 2 years ago...I waiting till Monday for my blood test results ...I don't know yet about folate,iron and b12 level but last few years I fell extremely tired and almost every night have tingling or numbness of my hands.Before I've start experience this I've been training every on gym so I was very active person till moment when I get stomach problems. GP diagnosed helicobacter pylori and I've had 3 types antibiotics and from that time my problems started I'm 36 year old man with two small kids and many times I'm not able to help for my wife. She even don't know what I experience. I've bought vitamin B12 Depot Hxydroxocobalaminacetat Rotexmedica from Germany . Should I buy methylocobalamin? Thanks for all for replies

[pvanderaa in reply to Beliverok]

I use the methyl- sublingual 5000 mcg tablets under the tongue to fill in between my weekly cyano jabs. Swallowing them doesn’t work as i have an absorption issue in my gut.

I take 2x at lunch and 2x more in the evening every day.

What are you doing for folic acid? B12 and folic acid work hand in hand and need each other to work correctly. I use the 800 mcg tablets and take 2x first thing in the morning, 2x at lunch and 2x in the evening. Don’t take more than 5 mg total per day.

[Foggyme Administrator in reply to Beliverok]

Hi Beliverok. Hydroxocobalamin is the B12 used for treatment of B12 deficiency in the UK and is suitable for the majority of people. Some (like me) find that methylcobalamin does not agree with them...and despite what you may read on the Internet, methylcobalamin is not a 'better' or more 'natural' form of cobalamin.

Here's a research paper about that:

ncbi.nlm.nih.gov/pmc/articl... (No Superior Forms of Cobalamin)

With respect to sublingual or oral tablets (as per pvanderaa reply)...the absorption rate from both is 1% - 3%. The absorption rate from injections is 100%. Tablets and sublingual work as top-ups for some people, and do nothing for others.

If you are self-injecting and have purchased your own B12, I'd suggest that you stick to injections - especially if you have neurological symptoms (in the UK, injections are the the recommended treatment).

The main thing is to work out what frequency of injection works for you. If symptoms start to return and then are relieved by an injection, the aim is to try and time the injections so that you inject before the symptoms return. May take a while to work out what frequency works for you - keeping a symptom diary can help (grade symptoms on a scale of one to ten then you can see when symptoms are getting better...or returning, and adjust the frequency of injections accordingly.

Good luck.

👍

P.s. I only spotted your reply by accident. If you want a particular person to see your reply, type in @ directly followed by the person user name and select the users name from the pop up box that appears...the user name will then appear in your reply in blue ( Beliverok ) and the person will receive a notification. If you are replying to one particular person's reply, click the blue 'reply' tab at the bottom of their reply and they will receive a notification via mail and be able to respond accordingly. 😉