I was diagnosed w PA last year although my antibodies test was negative. MyB12 had dropped below the magic number quite substantially after 8 weeks without oral supplements which had kept me just inside the minimum.
I bought the hydroxy, needles etc and managed to SI for a couple of months after my loading doses which just made me feel exhausted. I gained about a stone and I'm still not sure why but haven't been able to lose it, even when I began thyroid treatment under a private GP because again, my results were normal.
I had my genes looked at and I don't have the MTHFR but wondered if it was the hydroxy rather than methyl which was wrong but running my results through various analysers doesn't say to avoid anything other then "methyl donors"... I'm confused.
I hit a vein in my thigh and along with feeling even worse - exhausted, zero energy etc, I just stopped. Now I can't bring myself to begin again even though I know it won't have been the B12 alone. If I could SI once a week or alternate weeks I want to see how that works but I'm scared of more weight or even more fatigue. Has this happened to anyone else??