Hi. I have been getting B12 shots and iron infusion every other week since end of April following major Blood transfusion when hospitalized and diagnosed with hemoglobin of 4.5. They told me that the red blood cells were getting better and not as misshapen and getting more uniform in size so I figured everything was going along just fine. Now I am still being told that new red blood cells I'm making aren't normal in shape and size yet so may need further blood transfusions in future if I don't start producing normal oxygen carrying cells. How long does it take for new cells to return to normal? I am starting to get scared. Has anyone else's cells been abnormal in shape and size and is this a normal part of the body's attempt to start making red blood cells once treatment starts? I was too astounded and had to let this sink in before I was able to ask my oncologist-hematologist. I'll see him again for next treatment and more blood work the end of next week.