Homocysteine meaning ?: Hello everyone... - Pernicious Anaemi...

Pernicious Anaemia Society

32,623 members23,983 posts

Homocysteine meaning ?

Carae profile image
8 Replies

Hello everyone so extremely happy to find this intelligent site, so impressed, beyond❤️

I have a question about homocysteine result a nuerologist PA just gave now, she said it was low , 18, is that bad? She said she didn't know

I'm in the hospital and am being ignored re B12 issues. I'm a vegan 7 years

I sublingual B12 methyl high doses esp lately since Becoming ill a month ago thinking I have absorbsion problems

I had asked for mma also when I got to hospital 2 weeks ago she just said they didn't do it and just walked away..

I'm still confused can't look up things easily

Would greatly appreciate any info if I need b12 injections while here

B12 level was 1100 last week as I was mega dosing before I got here and she said folate was normal today, had to keep asking every day for these other tests and hense have folate and homocysteine today.

Thank you from the bottom of my heart for any advise❤️

Written by
Carae profile image
Carae
To view profiles and participate in discussions please or .
Read more about...
8 Replies
clivealive profile image
clivealiveForum Support

Hi Carae I'm not medically trained but perhaps the following "snippet" might help.

"B12 has two main jobs in the cell - one of them uses up a chemical called methylmalonic acid (MMA) the other uses up homocysteine (hCys). If the B12 isn't getting from the blood to the right places in the cell then one, or both, of these chemicals will not be used up and the amounts in the cell (and in the blood) will increase.

So a blood test for MMA and/or hCys can tell if the B12 is doing what it's supposed to be doing. If the levels of the two chemicals are normal then B12 is working properly. If the levels are raised then one explanation is that B12 isn't working properly (there are other possibilities - MMA can increase because of kidney disease, hCys can increase if folate is low).

But the key is that if either MMA or hCys is low then you know that B12 is definitely getting into the cell".

Carae profile image
Carae in reply toclivealive

Thank you so much I couldn't have figured that out am Very Ill

So it's not B12 not vegan related

Many many thanks

Thank you so much for your help

fbirder profile image
fbirder

Your B12 level is high, which is good; and your hCys level is low, which is also good. It really looks like, if you did have a low B12 problem, the sublingual methylcobalamin is doing what it is supposed to do.

If you had been low for a long time then it may take a while for the treatment to work fully.

Carae profile image
Carae

Thank you so much for your replies They are so v clear and helpful forward ❤️

Polaris profile image
Polaris in reply toCarae

cmim.org/pdf2014/funcion.ph...

The above latest BMJ research document might help convince your clinicians to do further tests.

Very best wishes for good treatment and a speedy recovery Carae

Carae profile image
Carae in reply toPolaris

Thank you

x

Polaris profile image
Polaris

I always understood that levels of homocysteine above 15 were high ? 🤔

"Most laboratories report normal homocysteine levels in the blood between 4 and 15 micromoles/liter (µmol/L). Any measurement above 15 is considered high. Optimal homocysteine levels are below 10 to 12.22 "

What are high homocysteine levels? - eMedicineHealth

emedicinehealth.com › page4_em

patrickholford.com/advice/h...

foodforthebrain.org/alzheim...

Carae profile image
Carae in reply toPolaris

Thank you so much I will verify figure she gave me hopefully tomorrow

x

Not what you're looking for?

You may also like...

MMA and homocysteine

I have been going to a hematologist. I brought lots of information from the pernicious anemia...
CW12 profile image

MMA and homocysteine tests

Hello everyone, I had the usual loading dose injections for my PA last October (after getting...
expatkerry profile image

Got Homocysteine lab back

Lab result of Homocysteine: 12.9 range: 0.0-15.0 Still waiting on the others. I couldn’t wait...
JennaShi profile image

Homocysteine

As i am in the "Normal Low Range" although my GP insists i am Normal B12 Range 155ng/L Range...
Advice1 profile image

Homocysteine and MMA connected?

Hi, apologies if this is a silly question. I checked my homocysteine recently and it was ok at 7.5...
GastritisB12 profile image

Moderation team

See all
Gambit62 profile image
Gambit62Administrator
Foggyme profile image
FoggymeAdministrator
taka profile image
takaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.