Nitrous oxide and B12 def: Went today... - Pernicious Anaemi...

Pernicious Anaemia Society

32,623 members23,983 posts

Nitrous oxide and B12 def

greenbexy profile image
5 Replies

Went today to see gastrolgist, he wants to do an endoscopy and colonoscopy (lucky, lucky me!). They offer sedation or laughing gas, I mentioned to the nurse doing all the talking that nitrous oxide could interfere with my already low vitamin B12, (thanks to the wealth of knowledge on here!) She looked at me as though I was talking a foreign language! "Hey doctor, have you ever heard of this?" He just looked perplexed (he did speak a foreign language) and shrugged. So I settled on the sedation, thanks very much.

As I booking the appointment the nurse came out telling that I was right about the nitrous oxide, thanked me for informing her but as I was only having a short procedure I would be okay.

Surely this would be alright if I didn't need B12 injections, and absorbing vits and iron as a 'normal' person, (hence the invasive procedures needed!) Am I right in thinking it could still damage my B12 levels even over a short period?

Written by
greenbexy profile image
greenbexy
To view profiles and participate in discussions please or .
Read more about...
5 Replies
Gambit62 profile image
Gambit62Administrator

nitrous oxide doesn't change your B12 levels it just converts B12 to a form that the body can't use - making it inactive.

I don't think I would want to use nitrous oxide at all though the amounts of B12 washing around in blood are probably such that it's only going to have a small impact on the total amount of B12.

greenbexy profile image
greenbexy in reply toGambit62

Would I still have B12 'washing around the blood' if I'm only on three monthly injections but probably need more, as I've still got pins and needles, shortness of breath and poor memory?

Gambit62 profile image
Gambit62Administrator in reply togreenbexy

you can be deficient at cell level even tough you have lots in your blood though also possible if it is a while since you had an injection that your levels are low- how long since injection? have you ever had levels measured and doyou know how they vary after maintenance shots?

greenbexy profile image
greenbexy in reply toGambit62

Had my loading doses between Christmas and New year, had my first maintenance injection on Monday. Levels before B12 were 152 (170-730). I went back to the doctors with evidence that I should be getting more before my first injection, he didn't read any and sent me off for vit D test :12 (50-250), Thyroid 'normal' and a referral to gastroenterology.

Feel tired still, but I have been trying to cut down on caffeine. Then started with pins and needles again yesterday, so I presume I need it more often, don't really know anymore. Feel like a hypochondriac at times...

Gambit62 profile image
Gambit62Administrator in reply togreenbexy

you are not a hypochondriac.

you are being under treated - return of symptoms shows that - but that doesn't necessarily mean that B12 levels in your blood being low. Normal range is no guide at all if you have had a B12 shot.

unfortunately I don't have a magic bullet for over-coming attitude, lack of time and ignorance of GPs.

Important thing here is that you didn't use nitrous oxide

Not what you're looking for?

You may also like...

Nitrous oxide and nitrox

Hello, lovely people, I wonder if you can help where Google has failed? I understand that those of...
spacey1 profile image

Nitrous Oxide & B12

I am just after some clarity on the subject and I know many of you here are very knowledgeable. I'm...
brighter84 profile image

Nitrous oxide question

Hello, What would happen if I were to have an accident (say a broken leg), and was offered nitrous...
Curlygal profile image

Nitrous Oxide

I just wanted to warn you all about the effect of nitrous oxide. Apparently it will oxidise all the...
BirdlessBox profile image

Does Nitrous Oxide Negate B12?

I was diagnosed with PA 12 years ago, but had the terrible fatigue and other symptoms for 10 years...
lindajanes profile image

Moderation team

See all
Gambit62 profile image
Gambit62Administrator
Foggyme profile image
FoggymeAdministrator
taka profile image
takaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.