I am newly diagnosed and put out a couple of recent posts - thanks to all for the feedback! Now I am stuck in a total rut because I have tried all three cobalamins (Cyano, Hydroxo and Methyl) and have difficulty tolerating each one. Cyano is the worst but the other two are pretty bad as well just in different ways.
I'm doing sub-q injections but have also tried sublingual Methyl tablets. I am unable to handle the side effects at any dose higher than 250 mcg no matter what the form.
I just ordered the kit from 23andme and hope to get more info to help me figure this all out. But given the long time frame before I get results back I'm feeling desperate to try something that might help me tolerate the B-12 right now. I am becoming more incapacitated and have been home bound for 3 months. I need to get back to work
I'm thinking of trying some Methylfolate but when I was first tested (before supplementing with B-12) my Folate Serum was 20.0 ng/mL which was good given a reference range of >3.0 (I'm in the U.S.). I have not been tested since injecting B-12 over the last 2 months.
-Should I only take Methylfolate if my Folate level is low or do some people just try the Methylfolate anyway to see if it helps them tolerate the B-12 and feel better overall?
-If I have my GP re-test the Folate to see if it has gone down are there any other tests I should do also like:
*Homocysteine and Ferritin (which have never been checked)
*MMA (which was originally high at 469 with reference range of 0-378)
*B-12 (which was originally 181 and went up to 1999 after one month of loading)
Any feedback would be much appreciated!! Thanks in advance!!