Pernicious Anaemia Society
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Quick question

Hi everyone, I've just joined this group, I have to go and have a b12 and folate test, just wanted to know if there's a particular time in the day or week that's optimum for results?

Also, as pa is auto immune, do you have flares like other auto immune conditions?

Just wondering as I've had symptoms for a long time, but I do have periods when I don't feel too bad but still get tired quickly, I have had lots of tests done in the last few years but the only thing that's ever come back is low platelet, low heamoglobin, low lymphocytes, low hematocrit. But doc says not to worry, (they were all just under range) and vit d of 35 which I had treatment for. It is affecting my work and being self employed it's becoming quite a problem.

Any advice greatfully received. 😊 Thanks in advance

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have a b12 and folate test, just wanted to know if there's a particular time in the day or week that's optimum for results?

Not really. For B12 the levels will be roughly the same as anytime (as long as you've not been supplementing). Folate might get raised a bit if you've taken a folic acid tablet that morning or eaten a huge bowl of spinach for breakfast. Having the blood taken first thing in the morning with no brekkies is probably best.

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Thanks, just wanted to check as I've noticed people have mentioned best times for other tests before. Thanks again 😊

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Do you have any advice as far as flares? I know you can have good and bad days, but what about really good days and downright terrible days? Does that fit the symptoms?

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Not for me. I feel about the same for a week after my jab, then things start going downhill at a steady pace.

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The auto-immune bit of PA is the thing that causes problems absorbing B12 - the symptoms are those of the underlying B12 deficiency that results so I wouldn't expect them to follow a 'flare up pattern - just because the symptoms are so far removed from the mechanism of the original auto-immune response

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