I have recently been diagnosed with rheumatoid arthritis and have been taking various drugs before and after diagnosis. A ppi(omeprazole) was prescribed to take before Naproxen (500mg twice daily) and methotrexate (10mg weekly) with 5mg folic acid 3 days later. I also have cocodamol if needed too. I try to avoid cocodamol (which gives me constipation!) and naproxen therefore ppi if I can...because I know it's best to limit their use alongside mtx. I have also had 5 steroid injections plus a week course of prednisolone since late December/January to help the widespread swelling/pain to subside asap!
My last blood test (5 weeks into mtx) revealed slight b12 deficiency -154. I actually asked for this (along with a cholesterol check!) to be tested as my symptoms were a-typical of b12 deficiency! I have been prescribed 50mg cyanocobalamin / day, orally (without actually seeing me and asking about my symptoms!) by my gp. I read the bottle which suggests an adult can take up to 3 a day and understand that these are readily bought over the counter so have decided to take more until I feel the benefit! I'd like to hear if anyone has had a similar experience and when it's best to take these i.e. : with or without food, early in the day, spaced throughout the day etc. ?
I have also read (in many reports) that omeprazole can be a reason to encourage b12 deficiency....even though my clinical nurse and my gp assure me that's not true!!!
I've also read that a low b12 and a raised folates blood test result suggests further tests should be done??
I realise I'm rambling on.....sorry 😆