Firstly thanks again to everyone who kindly took the time to respond with help and advice to my first post here last week.
In summary for people who haven't read that post or thread: I was diagnosed with hashimotos hypothroid almost 2 years ago, coeliac disease soon after. I have positive parietal cell antibodies and generally things seem to be pointing to B12 defiency/PA. Im 100% gluten free and taking levothyroxine but feeling more exhausted than ever. Have lost my job, am unable to go out for more than a couple of hours (and even then feeling awful) and I want my life back.
I have put together an action plan on the back of my reading, research, informal discussions with a nutritionist, a lab testing company and other knowledgeable people along with all the comments from the lovely people from here and thyroid forum last week.
Unfortunately part 1 of my plan has failed already! I contacted my endo to ask for his authorisation for B12 injections. I mentioned some of the things that forum member Polaris and others had mentioned that Docs should do even if tests show normal levels, if patient still exhibits symptoms. This was his response:
"I do believe that B12 levels can appear normal when someone is truly deficient. However it is difficult to sanction treatment or ask your GP to kindly administer this when the results look “okay” as they may not feel comfortable prescribing under those circumstance. Secondly I mentioned in the past methylation pathway defect tests – if these are abnormal then the type of B12 you require may be just as important – too much or the wrong type of B12 and/or both can cause more problems. Therefore suggest working through the problem with Nutritionist with results may be best solution."
Now I have mentioned these B12 injections to him previously also. So I do not wish to push the point with him as he has generally been quite helpful and empathetic. However I need to take some action, hence the plan I wrote at the weekend.
MTHFR testing is one of the points on my plan.
So my questions here are:
1) re the Endo's letter above - I did not realise there were different types of B12 that I could take! Could anyone shed any light on this? And re: "too much" B12 - I thought that the body just discharges what it doesn't need?
2) Methylation pathway testing. I looked into this a lot last week and have found a couple of companies that do genetic testing. I have found it gets very very complicated! One site I found though seemed simple enough "23andme". Has anyway any experience of using them? If so is it possible to just find out what is going on with my thyroid and any vitamin/mineral defiencies? i.e I want to find out what is wrong with me now so that I can work on fixing it, and not get a load of data telling me I might have heart disease in the future!
I hope those questions make sense, and would be grateful for any helpful advice. Thanks for reading.