Hypophosphatemia from b12 injections - Pernicious Anaemi...

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Hypophosphatemia from b12 injections

Perniciousgirl profile image
16 Replies

Has anyone else experienced Hypophosphatemia from b12 injections ?

Did lowering dose or frequency help or rather more intake ?

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Perniciousgirl profile image
Perniciousgirl
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16 Replies
wedgewood profile image
wedgewood

In over 14 years of reading messages on this forum daily , I’ve never heard of B12 injections causing hypophosphatemia .

Can be induced by certain drugs , but I’ve never heard it in relation to B12 injections . I’m interested to hear any affirmative answers .

Perniciousgirl profile image
Perniciousgirl in reply towedgewood

Ps. I had to add iron and increase vit D recently too, so b12 is not the only change to my regiment.

Perniciousgirl profile image
Perniciousgirl

thanks so much for the reply. I can’t seem to find any real evidence on it online either.

My gp suggested that because B12 injections stimulate red blood cell production, it increases phosphate demand for new cell formation which can temporarily lower serum phosphate as cells take it up for ATP production.

But perhaps he was just hypothesizing this for me because I do have a very sensitive electrolyte balance which seems to be disrupted pretty easily.

He suggested reducing the injections until I see the specialist, but I’m unsure now.

wedgewood profile image
wedgewood in reply toPerniciousgirl

I do hope that you find out the reason soon. Do let us know how you get on . We need all the knowledge that we can get .

Perniciousgirl profile image
Perniciousgirl in reply towedgewood

Thanks a mil. Will let you know what comes of it.

Nackapan profile image
Nackapan

If this is low BP problem I don't expect in most cases thd cause is found .

Was that diagnosed by a specific blood test ?

Also suspect what I'd any underlying problems I the first place .

As when your body undef any stress they come out

Predisposed to certain things.

My b..p was low .

I always have run on thr low side

110/70 90/ 70

Until recently it's gone way up??? Since treatment for b12 deficiency with b12 injections???

Will be interested to hear others experiences.

That's if I've got the meaning right

I had an emergency visit last year where the only thing they could note was low phosphate - I’d been on B12 injections for a few weeks at that point and was having heart palpitations as well as other “fun” reversing out symptoms.

It hasn’t happened since so I don’t know that I’d say causation?

Nackapan profile image
Nackapan in reply toPlatypusProfit8077

I do know that a large dose in one thing I.e B12 knock other things ouf of whack.Ivd never had to supplement iron before .

Started as ferritin levels dropped after initial loading doses of B12.

Heart palpitations i had went after ferritin levels Inncreased

I.m not sure phosphate has ever been tested even in A and E .

B12 wasn't either!!

Told I was having a panic attack when brain CT clear.

Also disbelieved i wasn't taking recreational drugs as pupils dilated .

I wasn't having s panic attack

PlatypusProfit8077 profile image
PlatypusProfit8077 in reply toNackapan

I really think that when doctors lose their empathy and curiosity, they should stop practicing medicine.

I understand they’re overworked and understaffed but no one wants to be in the E.D.

“Be curious, not judgemental.”

Perniciousgirl profile image
Perniciousgirl in reply toPlatypusProfit8077

I agree.

Perniciousgirl profile image
Perniciousgirl in reply toNackapan

It makes sense that large doses ( especially if deficient) could knock out others, depending on each persons utilization of each electrolyte etc. and of course with anemia it can be such a delicate balance

That sounds like such a horrible experience, sorry to hear, especially when you are dismissed as it having to do with anxiety.

Perniciousgirl profile image
Perniciousgirl in reply toPlatypusProfit8077

Thanks for the reply. That’s very interesting. Low phosphate can make you feel awful. I’ve been battling with reversing symptoms for several weeks ( I only found out from this platform that it was what I was experiencing). I guess it’s so hard to know what the cause is sometimes.

Susanemily profile image
Susanemily

i'm so sorry. How did you reverse your low phosphate level levels? I noticed I've been having issues over the years from the injections,most likely.

Perniciousgirl profile image
Perniciousgirl in reply toSusanemily

Hey. I just got the results So I haven’t had the chance to reverse it. Am adding electrolytes so far that incl. phosphate.

Peter2345556 profile image
Peter2345556

interesting post! I went back and checked my blood results. My doctor has been checking phosphate over the years and I see that my levels have been steadily declining over the past 5 yrs to the point where I am just above the min range. It might be possibly related to why someone is B12 def. For example I am gluten intolerant so this may also cause me to not absorb phosphorus just like many other vits and minerals such as b12. Being gluten intolerant I am not eating whole grains/ cereals/ milk which are good sources of phosphorus. Anyways time to munch on some pumpkin seeds ( very high in Phosphorus). 😀

Perniciousgirl profile image
Perniciousgirl in reply toPeter2345556

Thanks for the reply.

You are right, it may well be related to something like that.

That’s interesting yours may be due to your gluten intolerance. It makes sense

I looked up some of the top foods and I eat quite a lot of them really as a vegan ( tofu, seeds, lentils) but I’ll increase those, along with the electrolyte solution, and see what the specialist has to say about it.

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