Hypophosphatemia from b12 injections - Pernicious Anaemi...

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Hypophosphatemia from b12 injections

Perniciousgirl profile image
7 Replies

Has anyone else experienced Hypophosphatemia from b12 injections ?

Did lowering dose or frequency help or rather more intake ?

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Perniciousgirl profile image
Perniciousgirl
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7 Replies
wedgewood profile image
wedgewood

In over 14 years of reading messages on this forum daily , I’ve never heard of B12 injections causing hypophosphatemia .

Can be induced by certain drugs , but I’ve never heard it in relation to B12 injections . I’m interested to hear any affirmative answers .

Perniciousgirl profile image
Perniciousgirl in reply towedgewood

Ps. I had to add iron and increase vit D recently too, so b12 is not the only change to my regiment.

Perniciousgirl profile image
Perniciousgirl

thanks so much for the reply. I can’t seem to find any real evidence on it online either.

My gp suggested that because B12 injections stimulate red blood cell production, it increases phosphate demand for new cell formation which can temporarily lower serum phosphate as cells take it up for ATP production.

But perhaps he was just hypothesizing this for me because I do have a very sensitive electrolyte balance which seems to be disrupted pretty easily.

He suggested reducing the injections until I see the specialist, but I’m unsure now.

wedgewood profile image
wedgewood in reply toPerniciousgirl

I do hope that you find out the reason soon. Do let us know how you get on . We need all the knowledge that we can get .

Nackapan profile image
Nackapan

If this is low BP problem I don't expect in most cases thd cause is found .

Was that diagnosed by a specific blood test ?

Also suspect what I'd any underlying problems I the first place .

As when your body undef any stress they come out

Predisposed to certain things.

My b..p was low .

I always have run on thr low side

110/70 90/ 70

Until recently it's gone way up??? Since treatment for b12 deficiency with b12 injections???

Will be interested to hear others experiences.

That's if I've got the meaning right

I had an emergency visit last year where the only thing they could note was low phosphate - I’d been on B12 injections for a few weeks at that point and was having heart palpitations as well as other “fun” reversing out symptoms.

It hasn’t happened since so I don’t know that I’d say causation?

Nackapan profile image
Nackapan in reply toPlatypusProfit8077

I do know that a large dose in one thing I.e B12 knock other things ouf of whack.Ivd never had to supplement iron before .

Started as ferritin levels dropped after initial loading doses of B12.

Heart palpitations i had went after ferritin levels Inncreased

I.m not sure phosphate has ever been tested even in A and E .

B12 wasn't either!!

Told I was having a panic attack when brain CT clear.

Also disbelieved i wasn't taking recreational drugs as pupils dilated .

I wasn't having s panic attack

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