Hello All, I'm new here as I've just been diagnosed as having Biermer's disease, which I believe is another name for PA. I'm producing antibodies against intrinsic factor and my B12 is at 267, my ferritine is at 12 and my hemaglobin levels are just within the normal range, so not yet anemic, but very tired. I've been suffering with neurological disturbances for 6yrs now and my doctor doesn't understand why as at 267 my B12 is the low end of normal. She suggests that she tests me in 1 month, so basically she's waiting until I get really ill, I'm not entirely confortable with this even though she's the best doctor I've seen to date (and believe me, I've seen a few!) My question is, isn't there a 2 year delay between the B12 level showing and the real B12 levels at present because the vitamin is stocked in the liver? She also told me supplements wouldn't make any difference as the antibodies will stop me from absorbing so an injection would be needed. What's the difference between supplements, injections, sublingual and sprays? Is there a danger of over supplementing? I'm eating 100g of liver per day in an effort to stay upright.