Over many years my wellbeing has deteriorated to the point where, if I was 95, I'd accept the exhaustion, muscle fatigue (I can hardly walk upstairs), mental confusion and constant pain, weakness and pins and needles in my hands. I'd say to myself I'd had a good innings and if I died tomorrow, well, that was only to be expected.
But I'm 47, a single parent and my livelihood is at serious risk (I'm self employed).
I've been tested for everything (at different points I've been treated for Graves' disease and anaemia) but the overall trajectory has been the same. I've recently found out that ALL of my symptoms tally with B12 deficiency. As soon as I had a blood test I slapped on 5000 mcg B12 patches, not weekly as recommended, but daily. At the end of the week my pins and needles were not so severe and my energy levels were raised.
I fully expected to get the blood results to see a serious B12 deficiency but the level was 275 (range 197-886). And parietal cell autoantibodies were negative. The GP says I'm not deficient and he can say 'with certainty' that I don't have PA. I don't believe this is correct.
I did say that the PA Society believes anything under 500 should be treated and that the antibody test was only 50% effective but he said, 'In that case we'd treat everyone.'
I can carry on with the patches myself but advice on how often etc would be appreciated. I know you can't overdose on B12 but the patches also contain 10 other B vitamins, and maybe you can overdose on those. Should I also supplement folic acid, which is 6.1 (range 4.6-18.7) for serum folate?
I really would appreciate some advice as if the neurological symptoms become permanent I love my livelihood. Thank you