I was diagnosed with stage 3 primary peritoneal cancer in Sept 2009, when I had CA125 of over 4000 before treatment. I had successful chemo and surgery, finishing chemo in March 2010, and CT scan clear in April 2010. I had recurrence in peritoneum and liver, found in October 2010 and had a further successful course of chemo, after which liver appeared clear, but still some traces of metastases in peritoneum. CA125 has remained below 10 since I finished chemo in March 2011.
To cut a long story short, I took ibuprofen then diclofenac for a coincidental hamstring strain from April 2011 for 4 months, then after a 3 week break have been taking ibuprofen as an anti-cancer drug regularly since late August 2011, along with omeprazole to protect my stomach from the likely side effects of ibuprofen. I had been told I would be highly likely to relapse without treatment by Sept 2011, but my last CA125 was 6 two weeks ago.
Aspirin has been shown to be effective in many cancers to prevent spread - research published in March 2012, and from early research in the lab it is possible that ibuprofen is better. I had done my own research, and my GP agreed I should give it a try when I discussed it with her. I feel others should know about this. My consultant knows I am on ibuprofen, but said originally she could not recommend it, as there have not been trials.
The effect of aspirin and anti-inflammatory drugs like ibuprofen in preventing some cancers has been known since 2001. Why has this promising discovery not been followed up sooner?
I would like there to be widespread trials of this promising line of treatment, but there is apparently a lack of funds. I would like others to benefit as quickly as possible, and would like to start a campaign for a trial of ibuprofen or indeed aspirin in ovarian cancer after the initial surgery and chemotherapy, to try to prevent spread of the cancer. With my own experience so far I would favour ibuprofen.