CA125

[ElayneZ]

In May 2018 I was dx OC - Stage 3 - had hysterectomy and 18 weeks taxol & Carbo. Had first recurrence 18 months later. Then completed 9 months doxil & carbo Feb 2021. After pet scan which showed NED, I had 2 Pfizer vaccines in April and then started Lynparza. My CA 125 has increased monthly from 8 to 24 as of this week. NP says slight increases can be from covid vaccine and/or Lynparza. Has anyone else experienced slight increases after starting on PARP? Has it decreased? Thank you for sharing!

[Tesla_7US]

Yes, my CA 125 increased 30 pts and then dropped back down to normal. I was on Olaparib for 20 months before I recurred for the third time in 6 years. I'm having carbo only now and it's working well. I'm HGSE OC 3C somatic BRCA 1 HRD+.

[ElayneZ in reply to Tesla_7US]

Thank you so much for sharing! Very glad to know your CA125 did decrease back within normal. And too that the Carbo is working well for you. Take care. Blessings!

[Tesla_7US in reply to ElayneZ]

I'm amazed that after only two infusions carbo alone has knocked down my CA125 75%. This, statistically, implies I could be NED again after treatment. I'll then go on another PARP.