Update. Kind of odd, but Mom who has Stage 3c ovarian cancer, had a tremendous response from Carbo + Taxol first line treatment. Her CA125 plummeted from 3,000 to near 0 during her 4 month treatment. Even 1 month post treatment the CT scan showed no signs of cancer at all. The cancer spots on the outside of her colon (which they left during surgery) were even gone. However, 4 months post-treatment the cancer returned to the peritoneal lining and CA125 increased to 500. At this point it appears that Mom is platinum-resistant. Thus, last Friday she started Bevacizumab + Taxol and will continue this treatment every week for 2 months. I continue to take her to all of her appointments and monitor her side effects. Rash is the major side effect along with the typical taxol side effects including: nausea, headaches, and leg pain. We also discovered that potassium was not the issue with the leg pain, it was low magnesium. I requested that they run the entire comprehensive blood chemistry panel to identify the culprit, since her potassium level was seemingly normal. Her blood chemistry Mg level came back extremely low, which required an IV treatment. My apologies in advance for my delayed responses to you all, I am in my third year of law school with class everyday except Friday, which is when I travel downtown to take my mom to chemo all day. The weekends are always rough immediately following because Mom is sick from treatment and I am up late catching up on all my homework. Please let me know if any of you all had success with Avastin (Bevacizumab) or some other 2nd line treatment for platinum resistant ovarian cancer. Also, if you know how to deal with the terrible rash that occurs immediately following this treatment please also share any guidance.