My wife has low grade serous ovarian cancer, she was treated with Taxol, Carboplaxin and Avastin. We were told the Avastin had some serious side effects including bowel perforation. After her 3rd treatment, we had her admitted into the hospital with a bowel perforation. Currently she has been in the hospital for 3 weeks, having multiply issues. My wife is a long time survivor of Ovarian cancer. She was first treated for the disease 38 years ago and in remission for the entire time. She did develop cardiomyopathy due to chemo she received when she was 21. At any rate beware of the Avastin, hope others have not had this same experience. Wishing all of you brave ladies the very best.